A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy

Colonic Cancer Clinical Trial

Official title:

A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00280332
• Other study ID #: FUC
• Status: Completed
• Phase: N/A
• First received: January 20, 2006
• Last updated: May 9, 2008
• Start date: March 2006
• Est. completion date: November 2007

Study information

• Verified date: May 2008
• Source: Chinese University of Hong Kong
• Contact: n/a
• Is FDA regulated: No
• Health authority: Hong Kong: Department of Health
• Study type: Observational

Clinical Trial Summary

• To determine the prevalence of colonic neoplasm in patients who had previously undergone screening colonoscopy

• To determine the optimal time interval for re-screening in average risk individuals

• To determine potential baseline characteristics that predicts adenoma recurrence

Description:

Colorectal cancer (CRC) is the second commonest cancer in Hong Kong, and tends to be increasing. Screening for colorectal cancer can reduce the cancer incidence and mortality by detecting early lesions. However, the best interval for a follow up colonoscopy, particularly for those with normal baseline colonoscopy, remains largely unknown.

This study aim to determine the prevalence of colonic neoplasm in average-risk patients who had previously undergone screening colonoscopy and the optimal time interval for re-screening.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 560
• Est. completion date: November 2007
• Est. primary completion date: November 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 50 Years to 75 Years

Eligibility

Inclusion Criteria:

• Subjects who are previously participated in one of our two screening colonoscopy studies [Sung, Gastroenterol 2003; Leung, AJG 2004]

• Asymptomatic on first screening colonoscopy

• Age>50and <75

• No family history of CRC

• No other colonoscopy except the baseline screening colonoscopy

Exclusion Criteria:

• Subjects who refused consent

• Subjects who are not warrant follow up colonoscopy

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Colonic Cancer

Intervention

Procedure:
• colonoscopy
proform a follow up colonoscopy in the 5 year period from index colonoscopy

Locations

Country	Name	City	State
China	Endoscopy Center, Prince of Wales Hospital	Hong Kong (SAR)

Sponsors (1)

Lead Sponsor	Collaborator
Chinese University of Hong Kong

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The prevalence of advanced colonic adenoma in the re-screening population		5 year from index colonoscopy	No
Secondary	The time to adenoma adenoma development according to different baseline characteristics of patients and colonoscopy findings		5 years from index colonoscopy	No