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NCT05859581 Clinical Trial

The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer

Colon Cancer Clinical Trial

Official title:
To Explore the Value of Colon MRI in Assessing the Status of Retroperitoneal Resection Margin Following Beyond Complete Mesocolic Excision Surgery for Advanced Colon Cancer

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05859581
Other study ID # Colon MRI-2023-01
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date April 2, 2023
Est. completion date August 31, 2023

Study information
Verified date May 2023
Source Peking University Cancer Hospital & Institute
Contact Zhen Guan, MD
Phone 861088196825
Email 18801231091@163.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer. The main questions it aims to answer are: - Concordance between MRI suspected RPRM positive and pathologically confirmed positive. - Can RPRM-positive patients undergo beyond complete mesocolic excision (CME) surgery in order to achieve R0 resection? Participants will undergo colon MRI examination and once MRI suspects RPRM positive, they will receive beyond CME surgery.

Recruitment information / eligibility
Status Recruiting
Enrollment 29
Est. completion date August 31, 2023
Est. primary completion date August 31, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - primary colon adenocarcinoma confirmed by biopsy - preoperative CT suspecting retroperitoneal resection margin (RPRM) positive - received colon MRI scan - underwent beyond complete mesocolic excision surgery - sufficient clinical and pathological results Exclusion Criteria: - combined with other malignant tumors - simultaneous distant metastasis - definite invaded other organs or structures (T4b tumors)

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Beyond complete mesocolic excision surgery
If the participants were diagnosed with positive retroperitoneal resection margin (RPRM), they underwent beyond complete mesocolic excision surgery to ensure the R0 resection.

Locations
Country Name City State
China Beijing Cancer Hospital Beijing Beijing

Sponsors (1)
Lead Sponsor Collaborator
Peking University Cancer Hospital & Institute

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary Coincidence rate with pathological result Coincidence rate between MRI diagnosed retroperitoneal resection margin and pathologically confirmed positive within 2 weeks after surgery
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