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Clinical Trial Summary

To determine the Efficacy and Safety of camrelizumab and apatinib combined with chemotherapy (mFOLFOX6) for MSS/pMMR locally advanced colon cancer.


Clinical Trial Description

To determine the rate of tumor regression grade 2-4 at time of radical resection of MSS/pMMR colon cancer following neoadjuvant treatment.To determine the pathologic downstage rates at time of radical resection of colon cancer following neoadjuvant treatment, pathologic complete response (pCR) rates, R0 resection rate, 2 year Disease free survival, OS(overall survival) and adverse events, including perioperative complication and mortality rate. To determine the pathologic downstage rates and pCR rate of radical resection of MSI/dMMR colon cancer. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04625803
Study type Interventional
Source Zhejiang University
Contact Weijia Fang
Phone +86-571-87235147
Email weijiafang@zju.edu.cn
Status Recruiting
Phase Phase 2
Start date January 4, 2021
Completion date November 30, 2025

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