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Neoadjuvant FOLFOX Chemotherapy for Patients With Locally Advanced Colon Cancer

Colon Cancer Clinical Trial

Official title:
Neoadjuvant Chemotherapy for Non-metastatic Locally Advanced Colon Cancer: A Prospective Multicenter Randomized Controlled Trial

Clinical Trial Summary

The main cause of recurrence after surgical treatment of colon cancer is distant metastasis. Neoadjuvant chemotherapy has potential benefits of improving the effectiveness of chemotherapy. Preoperative chemotherapy may eradicate microscopic metastatic cancer cells earlier than adjuvant chemotherapy, reduce cancer cell spillage during surgery, and lessen the invasiveness of surgical resection. This randomized multicenter phase III trial is assessing whether preoperative chemotherapy improves oncologic outcomes of patients with locally advanced colon cancer.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03426904
Study type Interventional
Source Kyungpook National University Hospital
Contact Soo Yeun Park, MD
Phone +82-53-200-2166
Email psy-flower@daumm.net
Status Recruiting
Phase Phase 3
Start date October 24, 2018
Completion date December 28, 2029
View Details
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