Colon Cancer Clinical Trial
Official title:
Patient-Reminder Results in Patient-Initiated Promoting Colorectal Cancer Screening Via Colonoscopy
Colorectal cancer is the third most common cancer diagnosed and third leading cause of
cancer-related deaths in the United States for both men and women. The American Cancer
Society (ACS) estimates about 108,070 new cases of colon cancer and 40,740 new cases of
rectal cancer will be diagnosed, and about 49,960 deaths will occur as a result of this
devastating disease in 2008. Over the last 20 years, the death rate for this cancer has been
dropping as a result of screening and early detection of cancer. In 2007, ACS reported that
early-stage colorectal cancer had a survival rate close to 80%, and up to 9,632 deaths could
be prevented each year if eligible patients received screening when necessary. However,
despite the proven efficacy of colorectal cancer (CRC) screening, only about 50% of eligible
US patients are currently being screened.
Specific Aims
The central hypothesis of this proposal is that patient-initiated prompting of primary care
physicians of the patient's interest in screening will increase referrals for CRC screening.
The following three areas will be investigated during this research:
1. To determine whether a communication tool provided to patients will initiate a
conversation with their primary care physicians about CRC screening, especially via
colonoscopy.
2. To determine whether this tool will impact referral patterns for screening, especially,
although not primarily, among poor and underserved populations.
3. To determine whether differences exist in regard to patient-physician communication
patterns about screening among residents and faculties in the fields of internal
medicine and family practice clinics.
At the close of the investigators study, the investigators wish to organize quantifiable
data demonstrating how patient-initiated prompting of primary care physicians for CRC
screening increases early detection and decreases potential mortality from colorectal
cancer. This data will inform a second, larger study to pursue the questions surrounding
patient-initiated prompting in
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Screening
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT05551052 -
CRC Detection Reliable Assessment With Blood
|
||
Completed |
NCT03457454 -
Reducing Rural Colon Cancer Disparities
|
||
Recruiting |
NCT06006390 -
CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT04088955 -
A Digimed Oncology PharmacoTherapy Registry
|
||
Recruiting |
NCT06010862 -
Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors
|
Phase 1 | |
Terminated |
NCT01347645 -
Irinotecan Plus E7820 Versus FOLFIRI in Second-Line Therapy in Patients With Locally Advanced or Metastatic Colon or Rectal Cancer
|
Phase 1/Phase 2 | |
Completed |
NCT03390907 -
Hybrid APC Assisted EMR for Large Colon Polyps
|
N/A | |
Recruiting |
NCT03175224 -
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
|
Phase 2 | |
Completed |
NCT04079478 -
The AID Study: Artificial Intelligence for Colorectal Adenoma Detection
|
||
Active, not recruiting |
NCT04057274 -
Acute Effect of modeRate-intensity aerOBIc Exercise on Colon Cancer Cell Growth
|
N/A | |
Recruiting |
NCT03190941 -
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
|
Phase 1/Phase 2 | |
Not yet recruiting |
NCT05147545 -
Impact of Exercise and Hyperlipidic Meal on Free Circulating DNA in Patients With Metastatic Colonic Cancer and Healthy Subjects
|
N/A | |
Recruiting |
NCT05026268 -
The Laparoscopic Right Colectomy With Intracoroporeal Anastomosis
|
N/A | |
Not yet recruiting |
NCT03277235 -
Effect of a Resilience Model-Based Care Plan in Newly Diagnosed Colorectal Cancer Patients
|
N/A | |
Active, not recruiting |
NCT02959541 -
PK/PD Investigation of Calciumfolinat in Blood, Tumor and Adjacent Mucosa in Patient With Colon Cancer
|
N/A | |
Active, not recruiting |
NCT02730702 -
Colon Cancer Risk-stratification Via Optical Analysis of Rectal Ultrastructure
|
||
Completed |
NCT02810652 -
Perioperative Geriatrics Intervention for Older Cancer Patients Undergoing Surgical Resection
|
N/A | |
Recruiting |
NCT02577627 -
Multi-Indication, Retrospective Oncological Study to Validate the Accuracy in Predicting TTP by PrediCare in Patients Under SOC
|
N/A | |
Terminated |
NCT02628535 -
Safety Study of MGD009 in B7-H3-expressing Tumors
|
Phase 1 | |
Recruiting |
NCT02526836 -
Complete Mesocolic Excision With Central Vessel Ligation Compared With Conventional Surgery for Colon Cancer
|
Phase 2/Phase 3 |