Colon Cancer Stage III Clinical Trial
Official title:
Repurposing the Antipsychotic Drug Chlorpromazine as Adjuvant Therapeutic Agent for Resected Stage III Colon Cancer: A Pilot, Randomized, Open Label, Controlled Study.
chlorpromazine displays a series of remarkable bio-molecular effects in cancer cells, as inhibition of cell growth, nuclear aberrations, inhibition of the phosphoinositide 3-kinase/mammilian target of rapamycin (PI3K/mTOR) axis, induction of cytotoxic autophagy, inhibition of glutamate and DRD2 receptors. This study will evaluate the addition of chlorpromazine to the first-line therapeutic protocol in colon cancer stage III.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04907643 -
Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
|
N/A | |
Completed |
NCT00309530 -
Randomized Study on Adjuvant Chemotherapy and Adjuvant Chemo-Immunotherapy in Colon Carcinoma Dukes C
|
Phase 3 | |
Completed |
NCT04342676 -
Lymph Node Ratio and Kras Mutation in R Colon Cancer
|
Phase 3 | |
Enrolling by invitation |
NCT05179889 -
Adjuvant mFOLFIRINOX for High-risk Stage III Colon Cancer
|
Phase 2/Phase 3 | |
Recruiting |
NCT06108310 -
ArTificial inTelligence-based RAdiogenomics in Colon Tumors
|
||
Withdrawn |
NCT05310565 -
The Effects of Chiropractic in Adults With Colon Cancer
|
N/A | |
Not yet recruiting |
NCT04488159 -
Immunoscore as Decision Guidance for Adjuvant Chemotherapy in Colon Cancer
|
Phase 3 | |
Recruiting |
NCT05194878 -
Neoadjuvant FOLFOXIRI Versus Immediate Surgery for Stage II and III Colon Cancers
|
Phase 3 |