Measurement of Colloid Osmotic Pressure in Plasma and Interstitial Fluid in Children

Colloid Osmotic Pressure Clinical Trial

Official title:

Measurement of Colloid Osmotic Pressure in Plasma and Interstitial Fluid in Children

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01044641
• Other study ID #: 065816
• Status: Completed
• Phase: N/A
• First received: January 6, 2010
• Last updated: July 3, 2014
• Start date: December 2009
• Est. completion date: May 2013

Study information

• Verified date: July 2014
• Source: Haukeland University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway:National Committee for Medical and Health Research Ethics
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to identify normal values of colloid osmotic pressure in interstitial fluid and plasma in healthy children between 2 and 10 years.

Description:

Measurements of colloid osmotic pressure (COP) by sampling of interstitial fluid from subcutaneous tissue and plasma are well documented in animal models and human adult studies. COP plays a major role in transcapillary fluid balance and is valuable in fluid therapy planning in critically ill patients. There are no data regarding interstitial fluid COP values in neither sick nor healthy children. Sampling of interstitial fluid by the wick method in children who is under general anaesthesia (ear-nose-throat operations) gives the opportunity to identify normal COP values in this age group.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 99
• Est. completion date: May 2013
• Est. primary completion date: May 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 2 Years to 10 Years

Eligibility

Inclusion Criteria:

• Children from 2 to 10 years

Exclusion Criteria:

• Medication

• Ongoing illness

• Syndromes

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Colloid Osmotic Pressure

Locations

Country	Name	City	State
Norway	Haukeland University Hospital	Bergen

Sponsors (1)

Lead Sponsor	Collaborator
Haukeland University Hospital

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Colloid osmotic pressure		60 minuttes after wick insertion	No