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Contextualized Neuropsychological Rehabilitation for CNS Cancer Survivors: The ImPACT Program — ImPACT  

Cognitive Impairment Clinical Trial

Official title:
Contextualized Neuropsychological Rehabilitation for CNS Cancer Survivors: The "I'm Aware: Patients and Carers Together" (ImPACT) Program"

Clinical Trial Summary

The aim of the present randomized-controlled study is to evaluate the feasibility, acceptability, and preliminary efficacy of a novel, context-sensitive neuropsychological rehabilitation intervention for brain cancer survivors.

Clinical Trial Description

Cognitive impairment is the most common late effect in brain cancer survivors, with profound negative effects on quality of life, work ability, and socioeconomic outcomes. Still, there is no gold standard approach to treating cognitive impairment in brain cancer survivors. Furthermore, there is a dearth of research on interventions to treat cognitive impairment in brain cancer survivors, and the relatively few studied interventions have proven limited effects. Arguably, four key elements are missing from a majority of studied interventions:1) transfer of learning to real-world functional outcomes, 2) awareness training to enhance compensatory strategy use, 3) inclusion of carers that could enhance transfer of learning to the home, and 4) recognition of the inter-related nature of cognitive, neurobehavioral, and psychological functions. The "I'M aware: Patients and Carers Together (ImPACT)" program is a novel, context-sensitive neuropsychological rehabilitation intervention that targets the above mentioned missing elements in previous rehabilitation efforts. The present feasibility randomized-controlled study aims to evaluate the feasibility, acceptability, and preliminary efficacy of this program in brain cancer survivors with cognitive impairment in preparation for a subsequent large-scale randomized controlled trial. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05858359
Study type Interventional
Source Aarhus University Hospital
Contact Lisa M Wu, PhD
Phone +45 87 15 37 48
Email lisa.wu@oncology.au.dk
Status Recruiting
Phase N/A
Start date June 1, 2023
Completion date June 1, 2026
View Details
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