China Alzheimer's and Neurodegenerative Disorder Research — CANDOR  

Cognitive Impairment Clinical Trial

Official title: China National Clinical Research Center Alzheimer's Disease and Neurodegenerative Disorder Research

Status Recruiting

Clinical Trial Summary

This is a multi-center study that has three cohorts: 1) cognitive normal cohort (CN), 2) Alzheimer's disease cohort (AD) and 3) vascular cognitive impairment cohort (VCI). The goal of this study is to understand the risk factors of AD and VCI and to identify high risk patients for early intervention. It will collect demographic information, family history, medical history, neuropsychological tests, imaging studies and biological samples through standard and uniform procedures.

Clinical Trial Description

In this prospective study, we will recruit subjects into one of the three groups based on inclusion and exclusion criteria: 1) CN, 2) AD and 3) VCI. We will follow up with each of them subject at designated time points up to 2 years. We will collect demographic, medical, imaging (MRI and PET scans), genetic information and various biological samples (blood, saliva, urine and feces) during the study period. This study uses a case-control study design. The matched cases will have similar age, gender and education levels. By studying the relationship between risk factors of AD and VCI, we will establish norms and parameters in the Chinese population. ;

Related Conditions & MeSH terms

• Cognitive Dysfunction
• Cognitive Impairment
• Neurodegenerative Diseases

• NCT number: NCT04320368
• Study type: Observational
• Source: Beijing Tiantan Hospital
• Contact: Shiping Li, Doctor
• Phone: +86 15830116199
• Email: drlishiping@163.com
• Status: Recruiting
• Start date: July 8, 2019
• Completion date: December 31, 2024