Cognitive Impairment Clinical Trial
Official title:
A Review of Test Procedures From Different Health Care Professions With Regard to Their Suitability for the Early Detection of Cognitive Impairments in Persons Aged 60 and Older: A Validation Study
Purpose of the study The purpose of this study is to evaluate five tests to see if they are suitable for the early detection of cognitive impairment in people over the age of 60. These test procedures record the movement pattern and gait pattern, the reaction time, so-called instrumental activities of daily life (e.g. shopping or preparing meals), nutritional behaviour and the relevant sense of smell. The results are compared with those of a diagnostic procedure already in use.
Status | Recruiting |
Enrollment | 300 |
Est. completion date | September 30, 2023 |
Est. primary completion date | September 30, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 60 Years to 75 Years |
Eligibility | Inclusion Criteria: - Healthy individuals aged 60-75 years - Interested in participating in the study - Signing a written informed consent form Exclusion Criteria: - Persons who are not legally competent (Austrian adult protection law) - Clinical diagnosis of dementia or MCI (Mild Cognitive Impairment) - Clinical diagnosis of mental illness (e.g. depression or psychosis) - Reduced mobility (sidekick, wheelchair) - No compensation for visual or hearing impairment - Insufficient knowledge of German |
Country | Name | City | State |
---|---|---|---|
Austria | University of Applied Sciences, FH JOANNEUM | Graz | Styria |
Lead Sponsor | Collaborator |
---|---|
FH Joanneum Gesellschaft mbH | Austrian Research Promotion Agency |
Austria,
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* Note: There are 12 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Erlangen Test of Activities of daily living in Persons with Mild Dementia or Mild Cognitive impairment (ETAM) | For three Items the performance is evaluated on a seven-level scale (0-6 points). The execution of an item is subdivided into six sub-steps so that the test persons receive one point for each error-free sub-step. A four-step scale (0-3 points) was used for two items with a less complex structure (alarm clock and tea). The total value ranges from 0-30 points. | By completing the entire test set, an average of 2 hours | |
Primary | Brief Smell Identification Test (B-SIT) | The test person should recognize 12 different odorous substances and choose from a four-step multiple-choice question. A total odour score results from the number of correctly identified odours, whereby higher values stand for a better odour performance (>9 recognised odours). | By completing the entire test set, an average of 2 hours | |
Primary | Reaction test (TDS) | Eye to hand reaction, eye to leg reaction, complex reaction capability; the time required (seconds/milliseconds) for the completion is recorded. | By completing the entire test set, an average of 2 hours | |
Primary | Dual-Task-Assessment (DTA) | Measures the influence of a cognitive task on the gait pattern. Impaired subjects show a stronger change of different gait parameters. The gait speed, cadence, stride length, stride variance and gait phases are measured. | By completing the entire test set, an average of 2 hours | |
Primary | Mediterranean Diet Adherence Score (MEDAS) | 14-Elements-Screeningtool for the evaluation of the adherence to the Mediterranean diet. The maximum score is 14 points and indicates full compliance with the Mediterranean diet. | By completing the entire test set, an average of 2 hours | |
Secondary | Cognitive Functions Dementia (CFD) | A digital test set for the early diagnosis of dementia. It contains tests for verbal learning and memory skill, working memory, measurement of attention, cognitive flexibility, information processing speed, visuoconstruction, object naming and verbal fluency. | By completing the entire test set, an average of 2 hours |
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