Cognitive Assessment in Excessive Daytime Sleepiness: Electrophysiological Study.

Cognitive Impairment Clinical Trial

Official title: Cognitive Assessment in Excessive Daytime Sleepiness: Electrophysiological Study.

Status Completed

Clinical Trial Summary

Cognition was assessed using Minimental state examination (MMSE), Trail making tests A and B (TMT) tests, P300 and quantitative electroencephalography (QEEG) sleepiness was assessed using Epworth Sleepiness Scale (ESS), Karolinska sleepiness scale (KSS) and QEEG also polysomnography (PSG) was done for all participated subjects

Clinical Trial Description

*The study is a case control study included 40 subjects, divided into 20 cases suffering from Excessive daytime sleepiness and 20 healthy control group.

all participants were subjected to:

1. Careful history taking and Complete neurological examination.

2. Initial assessment of cognition and sleepiness by two scales which were done once before sleep: Epworth Sleepiness Scale (ESS) and Minimental state examination (MMSE)

3. Scales and neurophysiological studies done before and after sleep:Karolinska sleepiness scale (KSS), Trail making tests A and B (TMT), P300, and QEEG

4. Polysomnography (PSG)

• EEG was recorded for 20 minutes duration before and after sleep recording. In each EEG recording, alpha attenuation test (AAT) was done after 10 minutes of recording basal resting EEG, then the absolute power of 5 electrodes (CZ, T3, T4, T5, T6,) were studied in the following frequency bands: delta (0.5-3Hz), theta (4-7 Hz) and also the absolute power of (O1, O2) were studied in delta, theta and alpha (8-12 Hz) bands. ;

Related Conditions & MeSH terms

• Cognitive Dysfunction
• Cognitive Impairment

• NCT number: NCT03446066
• Study type: Observational
• Source: Kasr El Aini Hospital
• Status: Completed
• Phase: N/A
• Start date: January 12, 2015
• Completion date: December 23, 2017