Cognitive Impairment Clinical Trial
Official title:
Functional and Cognitive Impairment Prevention Through Early Physical Activity for Elderly Hospitalized Patients: a Randomized Clinical Trial
Verified date | September 2017 |
Source | Fundacion Miguel Servet |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The current model of care for the hospitalized elderly patients has been conditioned by many factors unrelated to the disease process that caused the hospitalization and usually worsen the outcome of hospitalization circumstances. Many times hospitalized elderly patients spend most of the time in bed (even higher than 83% of bed rest versus 4% of those who stand or are walking). These patients have their functional and physiological reserve reduced which makes them more vulnerable to the effects of being bedridden. The consequences are at multiple levels emphasizing the functional loss or cognitive impairment, longer stays, mortality and institutionalization, delirium, deconditioning, pressure ulcers and decreased caloric intake, social isolation, poor quality of life and increased use of resources related to health. Exercise training can prevent functional and cognitive decline and modify even the posterior trajectory.
Status | Active, not recruiting |
Enrollment | 370 |
Est. completion date | January 2018 |
Est. primary completion date | September 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 74 Years and older |
Eligibility |
Inclusion Criteria: - Age 75 years and older - Able to tolerate exercise - Able to ambulate, with or without personal / technical assistance or move unassisted in a wheelchair - Able to communicate - Non-elective admission to hospital Exclusion Criteria: - Severe dementia (GDS 7) - Duration of hospitalization <72 hours - Unwillingness to either complete the study requirements or to be randomized into control or intervention group - Unstable cardiovascular disease or other unstable medical condition - Terminal illness |
Country | Name | City | State |
---|---|---|---|
Spain | Complejo Hospitalario de Navarra. Department of Geriatrics | Pamplona | Navarra |
Lead Sponsor | Collaborator |
---|---|
Fundacion Miguel Servet |
Spain,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Changes in functional status after the intervention (Barthel Index) | Barthel Index | Baseline (Hospital Admiission), 1 and 3 months later | |
Primary | Changes in functional status after the intervention (Mini Mental State Evaluation, GDS Yesavage, Trail Making Test) | Mini Mental State Evaluation, GDS Yesavage, Trail Making Test | Baseline (Hospital Admiission) and 1 and 3 months later | |
Secondary | Quality of life (EuroQol Scale) | EuroQol Scale | Baseline (Hospital Admission), 1 and 3 months later | |
Secondary | delirium (Confusion Assessment Method, Delirium Rating Scale-Revised-98) | Confusion Assessment Method, Delirium Rating Scale-Revised-98 | Baseline (Hospital Admission),1 and 3 months later | |
Secondary | mortality | Days alive since admission to hospital | Baseline (Hospital Admission), 1 and 3 months later | |
Secondary | Use of health resources | New admissions to Hospital, admission to nursing homes, visits to General Practitioner | Baseline (Hospital Admission), 1 and 3 months later |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02122198 -
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
|
N/A | |
Recruiting |
NCT04356924 -
Psychological Treatment to Support the Consequences of Cognitive Impairment
|
N/A | |
Suspended |
NCT05542238 -
The Effect of Acute Exercise on Cardiac Autonomic, Cerebrovascular, and Cognitive Function in Spinal Cord Injury
|
N/A | |
Terminated |
NCT04493957 -
Evaluation of an Educational Program in the Prevention of the Driving Risks in Patients With Neurocognitive Disorders : ACCOMPAGNE
|
N/A | |
Recruiting |
NCT04792983 -
Cognition and the Immunology of Postoperative Outcomes
|
||
Completed |
NCT06029920 -
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
|
N/A | |
Not yet recruiting |
NCT05068323 -
Impact of Interictal Epileptiform Activity on Some Cognitive Domains in Newly Diagnosed Epileptic Patients
|
N/A | |
Completed |
NCT04426838 -
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad
|
N/A | |
Completed |
NCT04713384 -
Remote Bimanual Virtual Rehabilitation Post CVD
|
N/A | |
Recruiting |
NCT06284213 -
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium
|
||
Recruiting |
NCT06053775 -
Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)
|
N/A | |
Completed |
NCT03698695 -
A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers
|
Phase 1 | |
Not yet recruiting |
NCT05552729 -
Effects of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestinal Tumors
|
Phase 1/Phase 2 | |
Recruiting |
NCT03268109 -
COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old
|
||
Completed |
NCT03301402 -
Air Purifier to Improve Endothelial Function and Carotid Intima Thickness
|
N/A | |
Completed |
NCT03187353 -
IMProving Executive Function Study
|
Phase 4 | |
Completed |
NCT05395559 -
Prevalence and Recognition of Cognitive Impairment in Hospitalized Patients: a Flash Mob Study
|
||
Recruiting |
NCT04897334 -
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
|
N/A | |
Recruiting |
NCT04907565 -
Impact of Obesity on Post-operative Cognitive Dysfunction: Role of Adipose Tissue
|
||
Recruiting |
NCT05030285 -
Telehealth Psychotherapy for Anxiety in Persons With Cognitive Impairment
|
N/A |