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Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study

Cocaine Use Disorder Clinical Trial

Official title:
Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study

Clinical Trial Summary

The purpose of this research study is to measure synaptic density in the brain comparing individuals with cocaine use disorder to healthy controls.

Clinical Trial Description

Healthy controls (HC) will be studied as outpatient and undergo one MRI and one 11C-UCB-J PET scan along with neurocognitive tasks. Individuals with Cocaine Use Disorder (CUD) will complete the study as inpatients on our unit and undergo one MRI and two 11C-UCB-J PET scan along with neurocognitive tasks. Cocaine users will be asked to complete outpatient follow-ups twice a week for up to nine weeks following their inpatient stay. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04721418
Study type Observational
Source Yale University
Contact Marcella Mignosa, MD
Phone 203 974 7557
Email marcella.mignosa@yale.edu
Status Recruiting
Phase
Start date July 20, 2021
Completion date June 2026
View Details
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