Cocaine Abuse Clinical Trial
Official title:
Computer-Based Training in Cognitive Behavior Therapy
The computer-based training program (CBT for CBT) focuses on teaching basic coping skills, presenting examples of effective use of coping skills in a number of realistic situations in video form, and providing opportunities for patients to practice and review new skills while receiving substance abuse treatment.
In this behavioral trial 120 methadone maintained cocaine abusing individuals will be randomly assigned to either treatment as usual in a community-based clinic OR treatment as usual plus 8 hours of access to the 'CBT for CBT' computer program over a period of 8 weeks. Primary outcomes will be retention in treatment and reduction in cocaine use (percent days abstinent, confirmed by urine toxicology screens). The patients' ability to demonstrate coping skills through a computerized role-play evaluation will be a secondary outcome. A six-month follow-up will assess durability and/or delayed emergence of effects. ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01601743 -
Exercise as a Behavioral Treatment for Cocaine Dependence
|
N/A | |
Completed |
NCT00217997 -
Impulsivity, Brain Function, and Substance Abuse Treatment in Cocaine Dependent Individuals
|
N/A | |
Terminated |
NCT00142883 -
The Effects of GABA Enhancing Medications on Individuals Addicted to Cocaine - 3
|
N/A | |
Completed |
NCT00227903 -
Therapeutic Substance Abuse Treatment in Pregnancy - 1
|
Phase 2 | |
Completed |
NCT00842517 -
Long Term Maintenance of Drug Abstinence
|
Phase 1 | |
Completed |
NCT02563769 -
Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study
|
Phase 1 | |
Completed |
NCT01651377 -
Pramipexole as a Treatment for Cocaine Dependence
|
Phase 1 | |
Recruiting |
NCT00439049 -
Substance Abuse Pre-Treatment Screening Study
|
||
Completed |
NCT00249457 -
Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2
|
N/A | |
Completed |
NCT01401270 -
Prize Contingency Management for Cocaine-Dependent Methadone Patients
|
N/A | |
Recruiting |
NCT06177860 -
Clinical and Atherosclerotic Characteristics of Patients With ACS Associated With Cocaine Use
|
||
Completed |
NCT02393599 -
Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin
|
Phase 1 | |
Completed |
NCT02141620 -
n-Acetylcysteine and Cocaine
|
Phase 0 | |
Recruiting |
NCT00218023 -
Medications for Stopping Cocaine Dependence and Preventing Relapse
|
Phase 2 | |
Completed |
NCT00218075 -
Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence
|
Phase 2 | |
Recruiting |
NCT05857852 -
Low-Intensity Focused Ultrasound for Cocaine Use Disorder
|
N/A | |
Completed |
NCT00606801 -
Galantamine Effects on Cognitive Function in Abstinent Cocaine Users
|
N/A | |
Completed |
NCT00292123 -
Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse
|
Phase 1 | |
Completed |
NCT00318760 -
Effect of Clonidine on Responses to Imagery Scripts
|
Phase 1 | |
Completed |
NCT01651364 -
A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence
|
Phase 1 |