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Coagulation Defect; Bleeding clinical trials

View clinical trials related to Coagulation Defect; Bleeding.

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NCT ID: NCT06025708 Completed - Clinical trials for Coagulation Defect; Bleeding

Quantra QStat Sample Type Comparison

Start date: September 11, 2023
Phase:
Study type: Observational

This is a single center prospective observational study to compare QStat parameter measurements in arterial and venous blood samples collected in parallel from patients undergoing liver transplantation.

NCT ID: NCT05376462 Completed - Trauma Clinical Trials

Quantra® System With the QStat® Cartridge in Trauma

Start date: April 12, 2022
Phase: N/A
Study type: Interventional

This is a prospective, single-center, controlled, open label, trial randomized in two parallel groups designed to assess the Quantra QStat System in trauma patients.

NCT ID: NCT05290675 Completed - Clinical trials for Coagulation Defect; Bleeding

Quantra QPlus Sample Type Comparison

Start date: November 4, 2021
Phase:
Study type: Observational

This is a single center prospective observational study to compare QPlus parameter measurements in arterial and venous blood samples collected in parallel from patients undergoing cardiac surgery.

NCT ID: NCT03699813 Completed - Clinical trials for Coagulation Defect; Bleeding

ROTEM Versus aPTT/PT in Pediatric Surgery

Start date: February 2, 2015
Phase:
Study type: Observational

Hemocoagulation management in perioperative bleeding is nowadays based on standard coagulation testing: activated partial thromboplastin time (aPTT), prothrombin time (PT), fibrinogen, D-dimers, platelets. An interest about viscoelastic coagulation testing methods is rising - use of rotational thromboelastometry (ROTEM) is mentioned in the newest European guidelines for hemostasis management. ROTEM has more advantages then standard tests. However, both tests have only grade 1C recommendation, and most of trials have been done on adults. The goal of the study is to compare a relationship between standard tests and ROTEM in pediatric patients in perioperative period to find out which test has better correlation with clinical status, to compare therapeutic strategies and time necessary for gain both of tests and to compare the difference in blood loss and blood products consumption in group treated by ROTEM versus standard tests. Reduced blood loss and amount of blood products transfusion is expected to be found in ROTEM group, representing lowering risk for the patient, all due to early evaluation of hemocoagulation and targeted therapy guided by ROTEM.

NCT ID: NCT02622126 Completed - Clinical trials for Coagulation Defect; Bleeding

Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia

Start date: January 2016
Phase: Phase 2
Study type: Interventional

Maternal hypotension is the most frequent complication of a spinal Anesthesia. The prevention of spinal hypotension appears more likely to decrease the frequency and severity of associated adverse maternal symptoms than the treatment of established hypotension. Intravenous fluid administration prior to spinal anesthesia for caesarean section is accepted standard practice. The choice of fluid depends on individual and institutional habit, material cost (crystalloid is considerably cheaper) and the perceived relative benefits and risks. Uncommon but potentially serious adverse effect of colloids is impaired coagulation. Although pregnancy is associated with hypercoagulability, little is known about the effects of colloid preloading on coagulation in pregnant patients.