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Efficacy of Erenumab in Chronic Cluster Headache — CHERUB01  

Cluster Headache Clinical Trial

Official title:
Efficacy of Erenumab in Chronic Cluster Headache: A 10 Week Double-blind, Randomized, Placebo Controlled, Multicentric Trial.

Clinical Trial Summary

The main purpose of this study is to evaluate the efficacy of erenumab in participants with chronic cluster headache.

Clinical Trial Description

The purpose of this study is to determine the efficacy of erenumab in a loading dose of 280mg followed by 140mg after 4 weeks compared to placebo as a prophylactic treatment in patients with chronic cluster headache. This study has a 10-week 2-arm, randomized, double-blind, parallel- group, placebo-controlled design. Data from this study will provide important information if the blockade of the CGRP receptor with erenumab is an efficacious principle for the treatment of chronic cluster headache ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04970355
Study type Interventional
Source Charite University, Berlin, Germany
Contact
Status Completed
Phase Phase 2
Start date December 2, 2021
Completion date September 27, 2023
View Details
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