Closed-Loop Communication Clinical Trial
Official title:
Individualizing Mean Arterial Pressure of Head Trauma Injury Patients Using an Novel Automated System for Vasopressor Administration : a Randomized Controlled Trial
The goal of this randomized controlled trial will be to show that the use of a novel automated system to guide vasopressor administration in head trauma injury patients will results in more time spent with a mean arterial pressure (MAP) within the predefined MAP compared to patients managed without any automated system (manually management)
In head trauma patients, the maintenance of MAP within a very narrow range is desired to
avoid secondary ischemic diseases. However, the MAP needed to reach can vary over time based
on intracranial pressure. Additionally, it is well know that the nurses in the Intensive care
unit managed multiple patients simultaneously and cannot dedicate 100% of his-her time to
adjust vasopressor infusion and/or fluid administration. Using a novel automated system can
overcome this issue and may lead to more time in MAP target than the traditional management.
All patients will have the same automated system for fluid administration using the EV1000
monitoring using the AFM mode ( Assisted fluid management). This system will recommend to the
clinical when to administer a fluid bolus to optimize SV and SVV. So fluid administration
will be standardized in both groups. The only difference will be the management of MAP.
The goal will be to compare a treatment period of at least 3 hours during which the patient
will be under continuous noradrenaline infusion. This treatment time should be within the
first 48 hours of patient admission in the Intensive care unit.
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