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Cleft Lip clinical trials

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NCT ID: NCT06067854 Active, not recruiting - Clinical trials for Perioperative Analgesia in Neonates

Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery

Start date: January 1, 2022
Phase:
Study type: Observational

In retrospective data search the investigators will identified the cumulative consumption of opioid analgesics during surgery and 24 hours after surgery in neonate with cleft lips who underwent primary cleft lip repair surgery.

NCT ID: NCT05971914 Active, not recruiting - Clinical trials for Cleft Lip and Palate

Alveolar Cleft Hard- and Soft Tissue Reconstruction With an Autogenous Tooth Derived Particulate Graft

Start date: October 12, 2021
Phase: N/A
Study type: Interventional

The present study aims at clinical and radiographic evaluation of the safety and efficacy of Bonmaker ATB powder combined with a novel split thickness papilla curtain flap in the treatment of alveolar cleft defects.

NCT ID: NCT05940389 Not yet recruiting - Clinical trials for Unilateral Cleft Lip

Nasolabial Soft Tissue Esthetics and Maxillary Changes in Unilateral Cleft Lip and Palate Using PreSurgical Infant Orthopedics With Different Approaches

PSIO
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The nasal deformity is an abnormality in the appearance and structure of the nose in cleft patients having unilateral cleft lip and palate (UCLP). It involves the displacement of the lower lateral nasal cartilage, oblique and short columella, depressed dome, overhanging nostril apex, and deviated septum. Difficulty in breathing and smelling are the main problems of this deformity. Rhinoplasty for CLP patients is very complicated due to the complex nature of this type of deformity, especially in wide and bilateral cleft patients it is quite challenging.

NCT ID: NCT05929560 Completed - Clinical trials for Unilateral Complete Cleft Lip and Palate

Digital Impression in Neonates

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The goal of this [clinical trial] is to [explore the attitudes of guardians with different educational background regarding the technique of impression registration as well as the compliance to using feeding appliances ] in [neonates]. Researchers will compare [conventional impression technique to digital impression]

NCT ID: NCT05876169 Enrolling by invitation - Clinical trials for Cleft Lip and Palate

How Does Orthognathic Surgery Affect Jaw and Neck Motor Function?

Start date: September 6, 2022
Phase: N/A
Study type: Interventional

In a prospective longitudinal study design, details in jaw-neck kinematics and electromyography (EMG) activity changes in patients (women and men) referred for surgical correction of basal relations between the maxilla and mandible over time; pre-operative and during follow-up 8 weeks and 18 months after surgical correction will be evaluated. The results will contribute with novel insights on jaw-neck motor function before, in short- and long-term after the surgical process. We will have blinded evaluation of outcomes.

NCT ID: NCT05837780 Enrolling by invitation - Clinical trials for Unilateral Cleft Lip and Palate

Effect of Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients

Start date: January 3, 2023
Phase: N/A
Study type: Interventional

This study includes Three Dimensional Evaluation of Maxillary Arch Changes After Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients (Randomized Controlled Trial) Null hypothesis: there is no difference between using conventionally constructed nasoalveolar molding device and using digitally constructed nasoalveolar molding device

NCT ID: NCT05830006 Not yet recruiting - Cleft Lip and Nose Clinical Trials

Indications and Evaluation of Microfat Grafting in Cleft Lip Nasal Deformities

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

Aim of the work: The study will be conducted to investigate the efficacy of microfat graftinig in cleft lip nasal deformities especially in young patients and those adults who don't need major correction after rhinoplasty.

NCT ID: NCT05825170 Not yet recruiting - Lip, Cleft Clinical Trials

Evaluation of a HA Dermal Filler in the Treatment of Lip Deformity

FENTHA
Start date: November 10, 2023
Phase: N/A
Study type: Interventional

Early postnatal repair of cleft lip and palate aims at the development of the child through reconstruction of the face soon after birth. Cleft lip is the result of a defect in the fusion of the buds of the face by default of cell apoptosis of the embryonic neural crest constituting the skin and the labial mucosa. Lip surgery or cheiloplasty primary of unilateral and bilateral cleft lip and palate is carried out from the age of 6 weeks. At the end of the surgical treatment, we often observe small unsightly residual volumetric asymmetries. The choice is then either to surgically reduce a muscular part too voluminous by reducing locally the volume of the lip, or to increase the volume of the thinnest portion this second solution is made possible either by injecting fat or by injection of hyaluronic acid. By adulthood, patients with cleft lip have often undergone 10 or more defect-related surgeries and many desire less invasive options to improve any residual cosmetic imperfections. The first use of a temporary alloplastic injectable soft tissue filler, hyaluronic acid (HA), for upper lip augmentation in a patient with asymmetry after surgical cleft lip repair was reported in 2008. There are few publications on the use hyaluronic acid in complement to the surgical treatment of cleft lip and palate, but all reported promising results.

NCT ID: NCT05796336 Recruiting - Clinical trials for Cleft Lip and Palate

Two Methods of Lip Taping as a Presurgical Orthopedic Appliance

Start date: January 12, 2023
Phase: N/A
Study type: Interventional

A randomized clinical trial to compare the effectiveness of two methods of lip taping as a presurgical orthopedic appliances on maxillary arch dimensions in infants with bilateral cleft lip and palate.

NCT ID: NCT05790044 Not yet recruiting - Postoperative Pain Clinical Trials

Clonidine for Infra-orbital Nerve Block During Pediatric Cleft Lip Revision Surgeries

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Pain in children is usually an undertreated entity. Undertreating perioperative pain could lead to various metabolic, physiologic, and neurophysiological responses. The usual means of management i.e., opioids may increase the incidence of respiratory depression in this age group. Adequate postoperative analgesia in children is a vital part of perioperative care. Good pain relief minimizes oxygen requirement, reduces cardio-respiratory demands, and promotes early ambulation and recovery. Regional block given preoperatively in combination with general anesthesia provides good preemptive analgesia. It is associated with hemodynamic stability, rapid and complete recovery, and reduced analgesic requirement in postoperative period. Type of the study: A prospective randomized controlled double-blind study.