Evaluation of Micro-osteoperforation on Rate of Maxillary En-masse Retraction

Class II Division 1 Malocclusion Clinical Trial

Official title:

Evaluation of Micro-osteoperforation on Rate of Maxillary En-masse Retraction: A Randomized Controlled Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03764189
• Other study ID #: CEBD-CU-2018-11-41
• Status: Not yet recruiting
• Phase: N/A
• Start date: January 2019
• Est. completion date: November 2020

Study information

• Verified date: December 2018
• Source: Cairo University
• Contact: Nashwa abdel m mohamed, master
• Phone: 01020271313
• Email: dr.nashwa_87[@]live.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

accelerated anterior teeth retraction with the help of microosteoperforation procedure and miniscrews.

Description:

the study contains 2 groups each contains 13 subjects, A control group (anterior segment retraction with the help of miniscrews) and an intervention group ( anterior segment retraction with the help of miniscrews and microosteoperforation)

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 13
• Est. completion date: November 2020
• Est. primary completion date: November 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 16 Years to 30 Years

Eligibility

Inclusion Criteria:

• Females with an age ranging between 16-30 years.

• Malocclusion that requires bilateral extraction of the maxillary first premolars and anterior segment retraction; Angle class I mal-occlusion with bi-alveolar dental protrusions or class II division 1.

• Healthy dental and periodontal condition with a good oral hygiene

• Absence of degenerative conditions.

• Full set of permanent dentition.

Exclusion Criteria:

• Medically compromised patients.

• Previous orthodontic treatment

• Patients suffering from any congenital, hereditary or systemic diseases or asymmetries that might have an influence on tooth movement

• Chronic use of any medications affecting orthodontic tooth movement (eg: NSAIDs).

• Active periodontal affection or severe gingival inflammation.

Related Conditions & MeSH terms

• Class II Division 1 Malocclusion
• Malocclusion
• Malocclusion, Angle Class II

Intervention

Procedure:
• microosteoperforation
small holes made using large round bur

Locations

Country	Name	City	State
Egypt	Cairo University	Cairo	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

References & Publications (10)

Alfawal AMH, Hajeer MY, Ajaj MA, Hamadah O, Brad B. Evaluation of piezocision and laser-assisted flapless corticotomy in the acceleration of canine retraction: a randomized controlled trial. Head Face Med. 2018 Feb 17;14(1):4. doi: 10.1186/s13005-018-0161-9. — View Citation

Alikhani M, Raptis M, Zoldan B, Sangsuwon C, Lee YB, Alyami B, Corpodian C, Barrera LM, Alansari S, Khoo E, Teixeira C. Effect of micro-osteoperforations on the rate of tooth movement. Am J Orthod Dentofacial Orthop. 2013 Nov;144(5):639-48. doi: 10.1016/j.ajodo.2013.06.017. — View Citation

Alikhani, M., et al. Micro-osteoperforations: minimally invasive accelerated tooth movement. in Seminars in Orthodontics. 2015. Elsevier

Blanco, J., et al., Efecto de la administración sistémica del 1, 25 Dihidrxicolecalciferol sobre la velocidad del movimiento ortodóncico en humanos. Estudio Clínico. Revista Odontos, 2001. 8: p. 13-21

Collins MK, Sinclair PM. The local use of vitamin D to increase the rate of orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 1988 Oct;94(4):278-84. — View Citation

Cruz DR, Kohara EK, Ribeiro MS, Wetter NU. Effects of low-intensity laser therapy on the orthodontic movement velocity of human teeth: a preliminary study. Lasers Surg Med. 2004;35(2):117-20. — View Citation

Kau CH, Kantarci A, Shaughnessy T, Vachiramon A, Santiwong P, de la Fuente A, Skrenes D, Ma D, Brawn P. Photobiomodulation accelerates orthodontic alignment in the early phase of treatment. Prog Orthod. 2013 Sep 19;14:30. doi: 10.1186/2196-1042-14-30. — View Citation

McGorray SP, Dolce C, Kramer S, Stewart D, Wheeler TT. A randomized, placebo-controlled clinical trial on the effects of recombinant human relaxin on tooth movement and short-term stability. Am J Orthod Dentofacial Orthop. 2012 Feb;141(2):196-203. doi: 10.1016/j.ajodo.2011.07.024. — View Citation

Nicozisis, J., Accelerated Orthodontics With Alveocentesis. Princeton Orthodontics. Clin Orthod, 2012. 19: p. 1-4

Ribeiro GL, Jacob HB. Understanding the basis of space closure in Orthodontics for a more efficient orthodontic treatment. Dental Press J Orthod. 2016 Mar-Apr;21(2):115-25. doi: 10.1590/2177-6709.21.2.115-125.sar. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Rate of En-masse retraction	retracting six anterior teeth	three to six months
Secondary	Root resorption affecting the six anterior teeth.	Amount of root volume loss analyzed through CBCT software	three to six months
Secondary	Tipping affecting the anterior teeth.	Changes in angular measurements calculated through CBCT software	three to six months
Secondary	Extrusion of anterior teeth	Linear measurement changes in the clinical height using CBCT	three to six months