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The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on the Immune Function for Cirrhosis Patients — ELSDI  

Cirrhosis, Liver Clinical Trial

Official title:
The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on the Immune Function for Cirrhosis Patients

Clinical Trial Summary

In this study, the investigators compared the improvement of immune function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative immune function and improve patient prognosis.

Clinical Trial Description

The patients were enrolled according to the research criteria, and collected the general basic information of the patients. After the preoperative preparation was perfected, the same surgical team performed laparoscopic splenectomy and azygoportal disconnection, and the same nursing team performed the nursing after the operation. Then, patients received a unified treatment plan after surgery, including medication, other treatments and follow-up. During the treatment, the immune function related indicators of the patients were monitored before surgery, 3, 6, 12 and 24 months after surgery, including the counts of leukocytes, neutrophils, lymphocytes, and monocytes, and the levels of CD4+,CD8+,CD4+/CD8+, and CD19,CD20. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05338294
Study type Interventional
Source Northern Jiangsu People's Hospital
Contact Guo-Qing Jiang, MD
Phone +8651487373382
Email jgqing2003@hotmail.com
Status Recruiting
Phase N/A
Start date March 1, 2022
Completion date October 31, 2024
View Details
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