Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2

Cigarette Smoking Clinical Trial

Official title:

Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05958992
• Other study ID #: Substudy #2: UP-20-00744
• Status: Completed
• Phase: N/A
• Start date: August 25, 2020
• Est. completion date: May 1, 2022

Study information

• Verified date: July 2023
• Source: University of Southern California
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study assess the ways in which e-cigarette product characteristics, such as flavors and nicotine salts, impact user experience to inform potential regulations.

Description:

There are three primary objectives to the study: (1) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect product appeal across young adult e-cigarette users and middle-age/older adult smokers; (2) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect abuse liability in young adult e-cigarette users and the ability to resist smoking in adult smokers; (3) Determine the affect of product characteristics on e-cigarette nicotine delivery profile.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 461
• Est. completion date: May 1, 2022
• Est. primary completion date: May 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 21 Years and older

Eligibility

Inclusion Criteria:

Vapers/E-cigarette Users - Regular use of e-cigarettes/vaping devices containing nicotine

Cigarette Smokers

• Regular use of cigarettes containing nicotine

Exclusion Criteria:

• Pregnant or planning to become pregnant

Related Conditions & MeSH terms

• Cigarette Smoking
• Cigarette Use, Electronic
• Electronic Cigarette Use
• Vaping

Intervention

Other:
• E-cigarette
Participants will self-administer experimenter-provided e-cigarettes

Locations

Country	Name	City	State
United States	University of Southern California	Los Angeles	California

Sponsors (1)

Lead Sponsor	Collaborator
University of Southern California

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Subjective Appeal	This self-report measures of subjective product appeal will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the appeal rating, with lower scores representing lower levels of appeal and higher scores representing higher levels of appeal.	1 hour
Primary	Sensory Attributes	This self-report measures of product sensory attributes will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the sensory attribute rating, with lower scores representing lower levels of liking the sensory attribute and higher scores representing greater liking of the sensory attribute.	1 hour
Primary	Vaping Delay	Minutes delayed before purchasing time to vape an e-liquid.	1 hour