Cyanoacrylate Closure Versus Surgical Stripping for Incompetent Saphenous Veins — CASS  

Chronic Venous Insufficiency Clinical Trial

Official title: Randomized Controlled Trial Comparing the Clinical Outcomes After Cyanoacrylate Closure and Surgical Stripping for Incompetent Saphenous Veins

Status Recruiting

Clinical Trial Summary

The purpose of this study is to evaluate the non-inferior, clinical outcomes after cyanoacrylate closure comparing the surgical stripping for incompetent saphenous veins.

Clinical Trial Description

Varicose veins are highly prevalent. In western countries, an estimated 23% of adults have varicose veins, and 6% have more advanced chronic venous disease, including skin changes and healed or active venous ulcers. There are several modalities to treat varicose veins. Open surgical treatment with ligation and stripping of the saphenous vein, combined with excision of large varicosities, has been the standard of care for many years. Endovenous thermal ablation by radiofrequency ablation (RFA) or endovenous laser ablation (EVLA) has been shown to be a safe and effective alternatives with high long-term target vein closure rates. Although both techniques have gained broad acceptance in many countries, one major disadvantage of these techniques is the requirement for use of tumescent anesthesia to avoid the thermal injury of the surrounding structures. Cyanoacrylate closure for varicose veins has recently been introduced for treatment of the incompetent saphenous vein. ;

Related Conditions & MeSH terms

• Chronic Venous Insufficiency
• Occlusions Vein
• Venous Insufficiency

• NCT number: NCT03835559
• Study type: Interventional
• Source: Kyung Hee University Hospital at Gangdong
• Contact: Jin Hyun Joh, MD, PhD
• Phone: +82-2-440-6261
• Email: vascularjoh@gmail.com
• Status: Recruiting
• Phase: N/A
• Start date: April 10, 2019
• Completion date: February 1, 2021