Association of Thyroid Autoimmunity and Chronic Urticaria

Chronic Urticaria Clinical Trial

Official title:

Association of Thyroid Autoimmunity and Chronic Urticaria in Taiwan

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00737451
• Other study ID #: 96051
• Status: Completed
• Phase: N/A
• First received: June 30, 2008
• Last updated: March 26, 2012
• Start date: March 2008
• Est. completion date: November 2010

Study information

• Verified date: September 2009
• Source: Far Eastern Memorial Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Increase prevalence of thyroid autoimmunity is found in patients with chronic urticaria. About 5-34% of chronic urticaria patients is associated with the presence of thyroid autoimmunity who are euthyroid status whereas 5-10% of them with either hyperthyroidism or hypothyroidism.

Description:

There is no such report on the association of thyroid autoantibodies and chronic urticaria in Taiwan population yet. This study is designed to investigate the prevalence of thyroid autoimmunity associated with chronic urticaria in Taiwanese population. In addition, we intend to find out the change in the level of thyroid autoimmunity after the treatment in order to further understand their relationship. We also intend to find out the prognostic parameters in patients with the presence of thyroid autoimmunity and chronic urticaria.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 155
• Est. completion date: November 2010
• Est. primary completion date: November 2010
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• 18 years old and above

• skin itching for more than 6 months

Exclusion Criteria:

• pure physical urticaria, infectious diseases, and food or food addictive hypersensitivity, chronic infection

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Autoimmune Diseases
• Chronic Urticaria
• Skin Itching
• Urticaria

Intervention

Behavioral:
• blood sampling
blood sampling 10ml from the study subjects

Locations

Country	Name	City	State
Taiwan	Far Eastern Memorial Hospital	Pan-Chiao	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Far Eastern Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The prevalence of thyroid autoimmunity in chronic urticaria in Taiwan		one year	Yes