Chronic Thrombocytopenia Clinical Trial
Official title:
Cerebral Dysfunction in Chronic ITP With High Risk of Serious Bleeding Excluding Intracranial Hemorrhage.
Intracranial hemorrhage despite being rare, several chronic ITP patients experience moderate to severe behavioral problems including learning difficulties, memory affection .These changes could be due to the presence of minute capillary dysfunction
- First identify the presence of cognitive, behavioral and/or minimal neurological
deficit in patients with chronic ITP and correlate these changes with radiological
evidence of minimal CNS bleeding.
- Second investigate the correlation between these behavioral and/or minimal neurological
deficits and duration, site and severity of bleeding (a total of 200 patient of
persistently low platelet count < 20x 10 9 for at least more than one month duration).
- The aim is to assess the behavioral changes in chronic ITP patients, and to assess the
possible relation of such changes to duration and recurrence of very low platelet count
as well as pattern of bleeding excluding frank intracranial hemorrhage.
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Observational Model: Case-Only, Time Perspective: Prospective
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