Secretin Infusion for Pain Due to Chronic Pancreatitis

Status Completed

Clinical Trial Summary

- To determine if intravenous secretin administration in escalating doses three times daily for three days will improve the pain from CP at the time of infusion, after each infusion (1 to 3 hours), at Day 7 after infusion, and at Day 30 after infusion.

- To validate the safety of intravenous secretin administration at the dosage indicated in this study.

Clinical Trial Description

12 patients will be enrolled in this study. Patients will be only those treated at Dartmouth-Hitchcock Medical Center for the diagnosis of CP. The diagnosis of CP will be made by the PI based on standard clinical, radiographic and/or biochemical criteria. Patients must be taking prescribed opioid analgesics for the specific treatment of CP at the time of study enrollment. Only patients between the ages of 18-70 and capable of providing informed consent will be considered eligible for the study. ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01265875
Study type	Interventional
Source	ChiRhoClin, Inc.
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	December 2010
Completion date	April 2012

View Details

See also
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