Chronic Neuropathic Pain Clinical Trial
Official title:
Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Chronic Neuropathic Pain: Retrospective Study on a Cohort of 149 Patients at Rennes University Hospital, From January 2014 to December 2015
A retrospective, monocentric, observational, descriptive, open study of a cohort of 149 patients from January 2014 to December 2015
Neuropathic pain is a public health problem because of its prevalence reaching nearly 7% of
the general population and the effectiveness of current treatments often remains incomplete:
only 30-40% of patients are relieved of 50% of their pain by a pharmacological approach.
As early as the 1990s, stimulation of the motor cortex by implanted electrodes made it
possible to successfully treat certain chronic refractory neuropathic pain. In 1995 it was
reported that the application of repeated shocks by transcranial magnetic stimulation of the
motor cortex could induce an analgesic effect in a patient suffering from neuropathic pain.
This technique has proved its analgesic efficacy after an induction treatment over 5 days, in
the context of chronic pain (neuropathic or fibromyalgia), but all the patients are not
responders and there is currently, Of predictive criteria for response. It seems important to
continue studies on this non-medicinal, non-invasive therapy with no significant adverse
effects.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Enrolling by invitation |
NCT01437332 -
Molecular Mediators of Nerve Injury Signaling
|
N/A | |
| Completed |
NCT00214955 -
Study to Evaluate the Efficacy and Safety of ORAVESCENT Fentanyl Citrate for the Management of Breakthrough Pain
|
Phase 3 | |
| Terminated |
NCT00189059 -
Effects of Amitriptyline for the Treatment of Pain on Driving Performance and Cognition.
|
Phase 4 | |
| Terminated |
NCT02335489 -
A Post Market Cohort to Assess the Performance of the Spinal Modulation Neurostimulator System for the Management of Chronic Neuropathic Pain of the Foot and/or Lower Leg
|
||
| Recruiting |
NCT04936646 -
Study of rTMS Analgesic Effect in Chronic Neuropathic Pain,
|
N/A | |
| Terminated |
NCT01205516 -
Methadone in Neuropathic Pain
|
Phase 4 | |
| Terminated |
NCT04287075 -
Surgical Treatment of Chronic Neuropathic Pain
|
||
| Recruiting |
NCT05537935 -
Low Dose Naltrexone for Pain in Patients With HIV
|
Phase 4 | |
| Recruiting |
NCT05593237 -
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
|
N/A | |
| Terminated |
NCT00189072 -
Effects of Gabapentin in the Treatment of Neuropathic Pain on Driving Performance and Cognition
|
Phase 4 |