Chronic Myelomonocytic Leukemia Clinical Trial
Official title:
Identification of de Novo Fanconi Anemia Patients Using FANCD2 Western Blots
Verified date | November 2015 |
Source | Children's Oncology Group |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Observational |
This research study is studying identification of de novo Fanconi anemia in younger patients with newly diagnosed acute myeloid leukemia. Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to Fanconi anemia in patients with acute myeloid leukemia.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | |
Est. primary completion date | January 2100 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A to 21 Years |
Eligibility |
Inclusion Criteria: - Treated on COG-2961 or COG-AAML03P1 - At high risk of having Fanconi anemia, defined as meeting one the following groups of clinical criteria: - Group 1: Prolonged neutropenia after induction, severe regimen-related toxicity (mucositis, veno-occlusive disease, end-organ damage) - Group 2: Early non-relapse death (induction, consolidation) - Group 3: Small-for-weight, secondary malignancies |
Observational Model: Case-Only, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
United States | Children's Oncology Group | Monrovia | California |
Lead Sponsor | Collaborator |
---|---|
Children's Oncology Group | National Cancer Institute (NCI) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Identification of children at high risk of having Fanconi anemia | Up to 5 months | No | |
Primary | Identification of Fanconi anemia patients | Up to 5 months | No |
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