Early Intervention With Acalabrutinib in Patients With High Risk CLL

Status Withdrawn

Clinical Trial Summary

This study evaluates the effectiveness of acalabrutinib treatment in patients with chronic lymphocytic leukemia (CLL) deemed at high risk for Richter's Transformation (RT). This is a single arm study. Enrolled patients will initiate therapy with acalabrutinib and will dose continuously. While on study, subjects will be monitored monthly for the first 3 months, then every three months thereafter until disease progression, discontinuation due to toxicity, death, or study completion.

Clinical Trial Description

This is a multi-center, single arm, Phase II clinical trial to investigate the effectiveness of acalabrutinib treatment within 6 months of chronic lymphocytic leukemia (CLL) diagnosis for patients with CLL deemed at high risk for Richter's Transformation (RT). ;

Study Design

Related Conditions & MeSH terms

Chronic Lymphocytic Leukemia
CLL/SLL
Leukemia, Lymphocytic, Chronic, B-Cell

Clinical Trial Details

NCT number	NCT04660045
Study type	Interventional
Source	Weill Medical College of Cornell University
Contact
Status	Withdrawn
Phase	Phase 2
Start date	May 2022
Completion date	June 2026

View Details

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