Chronic Low-back Pain Clinical Trial
Official title:
Brain Imaging Biomarkers for Response to Spinal Cord Stimulation in Patients With Chronic Low Back Pain
In this protocol, "Brain imaging biomarkers for response to Spinal Cord Stimulation in patients with chronic low back pain," the investigators plan to perform brain mapping studies in 42 patients who are undergoing spinal cord stimulation (SCS) for chronic low back pain (CLBP) as part of the participants normal clinical care during a 2-year period. This imagining study is completed for research purposes. There is no standard of care imaging for the participants. This study requires two visits in total. During the baseline visit, participants will undergo imaging acquisition protocol and corresponding assessments. Participants will have another follow-up visit (potentially remotely) for final assessments two weeks after the SCS treatment. The objective of the study is to investigate potential imaging biomarkers that can predict response to the SCS treatment. Specifically, the investigators hypothesize that the connectivity of a certain region of the brain (specifically the subgenual cingulate) prior to SCS may serve as a possible pre-operative imaging-based biomarker on response to SCS. The findings of the study may further enhance investigators understanding of the connectivity between brain areas that are critical to the therapeutic response to SCS in CLBP patients and that can be used as a putative biomarker to select patients who may respond to SCS.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05963451 -
Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain
|
||
| Completed |
NCT04283370 -
A Study Protocol Comparing a Home Rehabilitation Program Versus e-Health Program in Low Back Pain
|
N/A | |
| Completed |
NCT04824547 -
Evaluation of Long-Term Continuity of Exercises in Low Back Pain Individuals
|
N/A | |
| Completed |
NCT04046419 -
In Turkish Version "Health Care Providers and Impairment Relationship Scale (HC-PAIRS)"
|
||
| Completed |
NCT04399772 -
COgNitive FuncTional Therapy+ for Chronic Low Back paIn
|
N/A | |
| Recruiting |
NCT05780021 -
Motivational Support Program in Chronic Low Back Pain After Multidisciplinary Functional Rehabilitation
|
N/A | |
| Completed |
NCT04555278 -
Combining Non-invasive Brain Stimulation and Exercise to Treat Low Back Pain
|
N/A | |
| Completed |
NCT04530071 -
Evaluation of Safety, Tolerability, and Efficacy of CordSTEM-DD in Patients With Chronic Low Back Pain
|
Phase 1/Phase 2 | |
| Not yet recruiting |
NCT06347328 -
The Benefits of Posterior Joint Infiltration in Chronic Low Back Pain
|
N/A | |
| Not yet recruiting |
NCT06080464 -
Clinician Satisfaction With the VERABAND™
|
N/A | |
| Not yet recruiting |
NCT04940715 -
Efficacy of Passive Joint Mobilization vs Mobilization With Movement on Pain Processing in Patients With Chronic Low Back Pain
|
N/A | |
| Recruiting |
NCT04683718 -
A First in Human Feasibility Study to Evaluate the Safety and Effectiveness of the BIOTRONIK Prospera SCS System With HomeStream Remote Management
|
N/A | |
| Recruiting |
NCT05724160 -
Using Non-Weightbearing Stationary Elliptical Machines for Patients With Chronic Low Back Pain
|
N/A | |
| Recruiting |
NCT06030128 -
Core Stabilization Exercise Therapy in Chronic Lower Back Back Management in Community Dwelling Older Adults
|
N/A | |
| Recruiting |
NCT05846087 -
Mobile App-delivered Sleep Therapy (SleepFix) for Individuals With Chronic Low Back Pain and Insomnia
|
N/A | |
| Active, not recruiting |
NCT05396014 -
The BEST Trial: Biomarkers for Evaluating Spine Treatments
|
Phase 4 | |
| Active, not recruiting |
NCT06140862 -
Ankle Spine Syndrome "RAFFET Syndrome II
|
N/A | |
| Completed |
NCT05512338 -
Motivation and Adherence to Exercise Recommendations
|
N/A | |
| Recruiting |
NCT05021146 -
Essential Oil for Chronic Low Back Pain
|
N/A | |
| Completed |
NCT05690178 -
Deep Tissue Massage in Office Workers With Chronic Low Back Pain
|
N/A |