A Diagnostic Study on Patients With Drug-induced Liver Injury

Status Not yet recruiting

Clinical Trial Summary

Clinical Trial Description

This study is a multi-center, prospective, non-interventional cohort study with an estimated enrollment of 600 patients with acute DILI. According to the inclusion and exclusion criteria, the RUCAM scale and/or expert evaluation, patients with a clinical diagnosis of acute DILI will be included in the study to establish a multi-center, prospective DILI cohort. Depending on the presence or absence of associated chronic liver disease, the patients will be divided into the basic DILI group with chronic liver disease and basic DILI group without chronic liver disease. All enrolled patients should complete at least six months of follow-up.

This research will propose a new or optimized DILI diagnostic scheme based on the analysis of the problems existing in the practice of RUCAM scale, the clinical characteristics and prognosis of DILI, the exploration of biomarkers, and all the comprehensive information of big data from Hepatox platform, and establish a big data-based diagnosis model or auxiliary diagnosis decision system. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04526548
Study type	Observational
Source	Drug Induced Liver Disease Study Group
Contact
Status	Not yet recruiting
Phase
Start date	October 2020
Completion date	October 2021

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