Effects of the Low-level Laser Therapy (LLLT) on Muscle Strength (MS) of the Patients With Kidneys Failure (KF)

Chronic Kidney Failure Clinical Trial

— LLLTMSKF  

Official title:

Effects of the Different Intensities of the Low-level Laser Therapy on Handgrip Test on Patients With Kidneys Failure: A Randomized, Controlled Clinical Trail

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02586376
• Other study ID #: LLLT-RENAIS-2015
• Status: Completed
• Phase: N/A
• First received: October 5, 2015
• Last updated: February 2, 2016
• Start date: October 2015
• Est. completion date: February 2016

Study information

• Verified date: February 2016
• Source: Federal University of Health Science of Porto Alegre
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

The low-level laser therapy (LLLT) has been used in many inflammatory disorders. More recently the LLLT was associated with an improvement in the muscle strength and endurance. But, these effects were described only in health or athletic individuals. In this randomized and controlled clinical trails, the investigators will study the effects of LLLT on muscle strength of the patients with kidneys failure on long time hemodialysis treatment. Additionally, investigators will explore three different intensities up the muscle strength.

Description:

This study will be conducing in a large hospital that is reference in kidneys disorders treatments. 16 patients will be randomized for placebo, 4J, 6J, or 8J low-level laser therapy (LLLT). The maximal voluntary contraction (MVC) will be test by handgrip test before and after de LLLT. One-week interval between the LLLT will gave to reduce the influence between the treatments. Moreover the endurance test will be use to evaluate the muscle oxidation impact of the LLLT.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: February 2016
• Est. primary completion date: January 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 30 Years to 60 Years

Eligibility

Inclusion Criteria:

• chronic kidney failure,

• long time hemodialysis treatment (>18 months)

Exclusion Criteria:

• any health disturbance that can reduces the handgrip test performance beyond to the produced by the chronic kidney failure.

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Chronic Kidney Failure
• Kidney Failure, Chronic
• Renal Insufficiency

Intervention

Device:
• 0J LLLT
Sham Low-Level Laser Therapy (Sham LLLT): perform with the machine off.
• 4J LLLT
4J Low-Level Laser Therapy (4J LLLT) irradiation will be perform with 4J.
• 6J LLLT
6J Low-Level Laser Therapy (6J LLLT) irradiation will be perform with 6J.
• 8J LLLT
8J Low-Level Laser Therapy (8J LLLT) irradiation will be perform with 8J.

Locations

Country	Name	City	State
Brazil	Fabrício Edler Macagnan	Porto Alegre	RS

Sponsors (1)

Lead Sponsor	Collaborator
Federal University of Health Science of Porto Alegre

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle Strength (Handgrip Test)		once a week throughout 4 weeks	No