Association of Apical Periodontitis With Chronic Kidney Disease

Status Completed

Clinical Trial Summary

This investigation is aimed to assess the prevalence and severity of apical periodontitis (AP) in different stages of CKD patients and its impact on the systemic (nutritional and inflammatory) markers was compared to healthy individuals.

Clinical Trial Description

105 CKD patients (35 early (EG), 35pre-dialysis (PDG) and 35 hemodialysis (HDG)groups and 105 age and gender matched healthy controls were assessed for prevalence and severity of apical periodontitis and oral disease burden . Inflammatory (hsCRP and ferritin) and nutritional (urea and creatinine) markers were estimated and eGFR was calculated for the study population. Logistic regression was used to determine the possible association between CKD and AP in study population and Linear regression was performed to evaluate the possible association between systemic markers and endodontic burden (EB) in experimental group. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05818657
Study type	Observational
Source	Postgraduate Institute of Dental Sciences Rohtak
Contact
Status	Completed
Phase
Start date	December 1, 2021
Completion date	December 31, 2022

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