The Impact of Pharmacist-led Mobile Application on Adherence in Chronic Kidney Disease Patients

Chronic Kidney Diseases Clinical Trial

Official title:

The Impact of Pharmacist - Led Mobile Application on Medication Adherence and Efficacy in Chronic Kidney Disease Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05168449
• Other study ID #: CL (2871)
• Status: Completed
• Phase: N/A
• Start date: September 17, 2022
• Est. completion date: December 5, 2023

Study information

• Verified date: February 2024
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the study is to assess the impact of pharmacist led mobile application on adherence and efficacy of medication in chronic kidney disease patients

Description:

This is a prospective randomized two group pharmacist-led interventional study that will be conducted in a private nephrology clinic. The study will involve introduction of the mobile phone applications to chronic kidney disease patients to improve their adherence to the prescribed medications.

Recruited patients will be randomly divided in two groups; intervention group and control group, with baseline evaluation of outcomes to be measured.

Control group will be provided with usual care. Intervention group will be provided in addition to the usual care, with an access to the mobile application after a simple training for app usage. Both groups will be followed for a period of 3 months.

The study will include the development, validation and the testing for evaluating the specially designed mobile application.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 86
• Est. completion date: December 5, 2023
• Est. primary completion date: December 5, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Stages 2-5 of chronic kidney disease

• Literate

• Ownership of android smart phone compatible with the application

• Poly-pharmacy

Exclusion Criteria:

• On dialysis due to loss of kidney function

• Pregnancy due to altered physiology

Related Conditions & MeSH terms

• Adherence, Medication
• Chronic Kidney Diseases
• Kidney Diseases
• Renal Insufficiency, Chronic

Intervention

Other:
• Mobile Application
mobile phone applications directed to chronic kidney disease patients to improve their medication.

Locations

Country	Name	City	State
Egypt	Private Clinic	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in medication adherence	Using a medication adherence questionnaire.	Change from baseline at 3 months
Secondary	Change in estimated glomerular filtration rate/ creatinine clearance	Calculated using serum creatinine lab results obtained from clinic.	Change from baseline at 3 months
Secondary	Change in systolic and diastolic blood pressure	To be measured in clinic.	Change from baseline at 3 months
Secondary	Change in HbA1c	Lab results obtained from clinic.	Change from baseline at 3 months
Secondary	Change in mobile application usability and acceptability by patients	Using System Usability Scale (SUS) questionnaire. (scale 0-100 with higher score meaning better usability)	Change from baseline at 3 months