Chronic Kidney Diseases Clinical Trial
Official title:
Sexual Dysfunctions in Female Patients With Chronic Kidney Disease
A myriad of sexual problems affect men and women with chronic kidney disease (CKD), including
decreased libido, erectile dysfunction, dysmenorrhea, and infertility. Menstrual
abnormalities are common in CKD and many women are an-ovulatory.
Sexual dysfunction in CKD is multifactorial including hormonal alterations along with
vascular, neurologic, psychogenic, and other factors, such as medications, contribute to the
development of sexual dysfunction. Sexual dysfunction in females is mainly due to hormonal
factors and manifests mainly as menstrual irregularities, amenorrhea, lack of vaginal
lubrication, and failure to conceive.
The study will be conducted on 100 female patients divided in to two equal group:
1. Group A: The patient group include 50 female patients with chronic renal failure (eGFR
<15ml/min/1.7m2 )
2. Group B: The control group including 50 healthy females age matched with the patient
group.
The Female Sexual Function Index (FSFI) will be used to assess sexual function. This index
includes 19 questions related to 6 parameters: sexual desire, sexual arousal, lubrication,
orgasm, sexual satisfaction and dyspareunia. A face-to-face inter-view with each participant
in which the FSFI questions will be verbally asked and answered and compare between both
groups in sexual activity and effect of chronic kidney disease on sexuality.
Duration of chronic kidney disease, duration of dialysis ,number of sessions of dialysis per
week, medical treatment, haemoglobin,creatinine level will be fulfilled.
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