Novel Equation for Estimating Resting Energy Expenditure

Chronic Kidney Disease Clinical Trial

Official title:

Novel Equation for Estimating Resting Energy(REE) Expenditure in Chronic Kidney Disease(CKD) 3-5 Stages Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03377413
• Other study ID #: REE equation
• Status: Completed
• Start date: December 14, 2017
• Est. completion date: February 1, 2020

Study information

• Verified date: October 2020
• Source: Peking University First Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations are not applicable to CKD patients,so we aim to develop and validate a equation for estimating resting energy expenditure in CKD patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 300
• Est. completion date: February 1, 2020
• Est. primary completion date: January 31, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• CKD 3-5 stages

• Age:18-80 years old

Exclusion Criteria:

• Dialysis and kidney transplantation;

• Acute complications to hospitalization

• 1 month prior to the study;

• Acute or chronic infections, cancer and other wasting diseases in the past year;

• Thyroid dysfunction;

• Acute onset of podagra; Musculoskeletal diseases;

• Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD);

• History of hormonal drugs use;

• During pregnancy or lactation

Related Conditions & MeSH terms

• Chronic Kidney Disease
• Kidney Diseases
• Renal Insufficiency, Chronic
• Resting Energy Expenditure

Locations

Country	Name	City	State
China	Renal Division and Institute of Nephrology, Peking University First Hospital	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking University First Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Novel equation development	Developed equation for estimating REE in CKD 3-5 stages patients	September 1, 2017 to June 1, 2018
Primary	Novel equation validation	Validate the noval equation with REE obtained by indirect calorimetry (IC).	June 1, 2018 to March 1, 2019