Chronic Kidney Disease Clinical Trial
Official title:
The Prospective Cohort Study to Investigate the Role of Plasma Triglyceride/High-Density Lipoprotein Cholesterol Ratio To Predict Cardiovascular Outcomes in Chronic Kidney Disease.
The Triglycerides (TG) to High Density Lipoprotein Cholesterol (HDL-C) ratio is a feature of insulin resistance and an independent predictor of cardiovascular risk. The investigators aimed to evaluate the relationship between TG/HDL-C ratio and the endothelial functions in patients with CKD.
Cardiovascular disease (CVD) risk is substantially increased in subjects with chronic kidney
disease (CKD).The reasons for the elevated risk of CVD in patients with CKD are not fully
elucidated. There is not a good prognostic tool for the prediction of increased
cardiovascular risk in CKD. A simple, widely available, relatively inexpensive, and
generally reproducible marker to predict the CVD risk in subjects with CKD is needed.
The Triglycerides (TG) to High Density Lipoprotein Cholesterol (HDL-C) ratio is a feature of
insulin resistance and an independent predictor of cardiovascular risk. No study has been
performed so far, to evaluate the role of TG/HDL ratio to predict the CVD risk in patients
with CKD.
This study is designed to evaluate the relationship between TG/HDL-C ratio and the
endothelial functions in patients with CKD.
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Observational Model: Cohort, Time Perspective: Prospective
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