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Acute Effects of Cinacalcet on Arterial Stiffness and Ventricular Function in Hemodialysis Patients — ECIRA  

Chronic Kidney Disease Clinical Trial

Official title:
Acute Effects of Cinacalcet on Arterial Stiffness and Ventricular Function in Hemodialysis Patients

Clinical Trial Summary

The primary objective is to determine whether reduction of serum calcium concentration by cinacalcet leads to reduction of mean blood pressure adjusted c-fPWV. The secondary objectives are to study the effects of calcium reduction on 1) carotid-radial PWV (c-rPWV), 2) common carotid artery (CCA) biomechanics, 3) pulse wave profile and cardiac function.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator)

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01250405
Study type Interventional
Source Laval University
Contact
Status Completed
Phase Phase 4
Start date May 2012
Completion date April 2014
View Details
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