Chronic Kidney Disease Clinical Trial
Official title:
Effects of Progressive Resistance Training During Haemodialysis on Muscle Quantity and Function in Patients With Chronic Kidney Disease
The purpose of this study is to investigate the effects of a 12 week progressive resistance
training during haemodialysis on muscle quantity and physical functioning in chronic kidney
disease patients receiving maintenance haemodialysis.
It is hypothesised, based on previous literature involving similar resistance training
protocols in other catabolic conditions, that the resistance training will result in a
significant increase in muscle quantity as well a physical function.
Muscle wasting is common in patients with chronic kidney disease and has been associated
with decreased ability to complete activities of daily living, increased hospitalisation and
therefore and decreased quality of life.
In other catabolic conditions, such as cancer or rheumatoid arthritis, exercise is an
established treatment to reverse muscle wasting. It is uncertain whether exercise has this
effect in the chronic kidney disease population due to an altered hormone system that may
prevent the anabolic effects of exercise from occurring. However, progressive resistance
training, which is exercise that is most effective at eliciting an anabolic response has not
been effectively carried out with haemodialysis patients.
Therefore, this study aims to investigate whether or not a twelve week intradialytic
progressive resistance training programme will have an effect on muscle quantity, physical
function and quality of life in patients receiving maintenance haemodialysis.
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Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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