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Chronic Interstitial Cystitis clinical trials

View clinical trials related to Chronic Interstitial Cystitis.

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NCT ID: NCT06299683 Recruiting - Clinical trials for Interstitial Cystitis

Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work. Emotional suffering is common in IC/BPS and known to make physical symptoms worse, and studies show patient sub-groups respond differently to treatment. Individuals with IC/BPS have distinct subgroups, or "phenotypes," largely characterized by the distribution of pain throughout the body. Supported by our preliminary evidence, the overall goal of this project is to assess how IC/BPS phenotype may affect response to two different therapies often given without regard to patient phenotype, pelvic floor physical therapy (PT) and cognitive-behavioral therapy (CBT) for IC/BPS.

NCT ID: NCT06013449 Not yet recruiting - Clinical trials for Interstitial Cystitis

Efficacy of Pulsed Electromagnetic Field and Heparin/Bupivacaine Instillations

Start date: July 2024
Phase: N/A
Study type: Interventional

The objective of this study is to test the idea that Pulsed Electromagnetic Field (PEMF) therapy will serve as a safe therapeutic modality that can effectively be administered simultaneously with bladder instillations of a bupivacaine-heparin cocktail to improve the chronic pain and/or associated symptoms of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) patients. The study team will distribute the PEMF device to female adults with IC/BPS who have been prescribed bladder instillations of bupivacaine-heparin to see if PEMF therapy in conjunction with bladder instillations of heparin and bupivacaine may be more effective in reducing pain levels and symptomatology of IC/BPS than instillations alone.

NCT ID: NCT05744908 Completed - Clinical trials for Chronic Interstitial Cystitis

Pentosan Polysulfate Treatment's Effectiveness

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To examine the relationship between symptoms and quality of life before and after oral pentosan polysulfate (PPS) treatment in cases diagnosed with interstitial cystitis/painful bladder syndrome (IC/BPS).

NCT ID: NCT05149573 Recruiting - Clinical trials for Interstitial Cystitis

Investigation of PEMF Therapy for Female Patients With IC/BPS

Start date: August 29, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to gather information about the safety and effectiveness of the non-pharmacological (non-drug), non-invasive treatment known as low-frequency pulsed electromagnetic field (PEMF) therapy. The study team will distribute the PEMF device to female adults with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) to measure its ability to decrease bladder and pelvic pain as well as other urinary symptoms associated with IC/BPS. There are two sequential Aims in this study and subjects will be recruited to participate in only one Aim. In both Aims, data will be collected at baseline/enrollment, 4-weeks after using PEMF therapy, and 8, 12, and 16 weeks post-enrollment.

NCT ID: NCT04734106 Not yet recruiting - Clinical trials for Interstitial Cystitis

Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis

Start date: July 2024
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of super-concentrated, freeze-dried aloe vera capsules for treatment of interstitial cystitis.

NCT ID: NCT04540887 Completed - Clinical trials for Interstitial Cystitis

PEMF Therapy to Treat Interstitial Cystitis/Bladder Pain Syndrome

Start date: February 24, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to gather information from the investigation of a non-pharmacological (non-drug) treatment known as low frequency pulsed electromagnetic field (PEMF). The study team will be distributing the PEMF therapy to female subjects with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) to measure its ability to decrease pelvic pain. The results, from multiple questionnaires and voiding diaries, will be compared when participants are enrolled for treatment, at 4 weeks after using PEMF therapy, and 12 weeks post-enrollment.

NCT ID: NCT04275297 Completed - Clinical trials for Interstitial Cystitis

Optimizing Psychosocial Treatment of Interstitial Cystitis/Bladder Pain Syndrome

Start date: July 13, 2020
Phase: N/A
Study type: Interventional

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work. Emotional suffering is common in IC/BPS and known to make physical symptoms worse, and studies show patient sub-groups respond differently to treatment. By creating and testing a psychosocial intervention specific to IC/BPS, we will learn if this intervention improves patient wellness, who the intervention works best for, and how the body's pain processing influences outcomes.

NCT ID: NCT03143920 Terminated - Clinical trials for Painful Bladder Syndrome

Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder

HBOTCICrUTI
Start date: November 1, 2017
Phase: Early Phase 1
Study type: Interventional

Pilot study to determine feasibility for treating patients with two chronic inflammatory conditions of the urinary bladder: chronic interstitial cystitis and recurrent urinary tract infections using a standardized hyperbaric oxygen treatment plan. Presently there are no good treatments for these conditions and hyperbaric oxygen may be a safe and readily accessible therapy as it has proven successful an another type of chronic inflammatory condition of the urinary bladder known as "radiation cystitis". The study will determine if patients will consider this an acceptable treatment for their conditions and that it is well tolerated.

NCT ID: NCT02858453 Active, not recruiting - Clinical trials for Interstitial Cystitis

Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome

LEADERSHIP 301
Start date: July 2016
Phase: Phase 3
Study type: Interventional

This study evaluates the effects of two doses of oral AQX-1125 on bladder pain and other urinary symptoms in subjects with interstitial cystitis/bladder pain syndrome. Participants will receive either 100 mg AQX-1125, 200 mg AQX-1125 or placebo for the first 12 weeks of the study. After 12 weeks, all participants will receive either 100 mg or 200 mg AQX-1125 for 52 weeks.

NCT ID: NCT02331472 Completed - Clinical trials for Chronic Interstitial Cystitis

The Efficacy of Urine Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome (Pilot Study)

Start date: February 3, 2015
Phase:
Study type: Observational [Patient Registry]

This study is to evaluate the efficacy of urine biomarker in patients with interstitial cystitis/painful bladder syndrome