Resistance to Lamivudine in HBV Egyptian Patients

Chronic Hepatitis B Virus Treatment Clinical Trial

Official title: Pretreatment and On-treatment Indicators of Virologic Breakthrough in Chronic HBV Egyptian Patients Receiving Lamivudine Therapy

Status Completed

Clinical Trial Summary

On treatment parameters for Lamivudine resistance in HBV treated Egyptian patients

Clinical Trial Description

Primarily: To study the correlations between the following parameters in adult Egyptian patients with chronic viral hepatitis B before treatment:

• ALT.

• HBeAg.

• HBV-DNA by quantitative PCR.

• Biopsy (if possible). Secondarily: After receiving lamivudine therapy we will identify the impact of these parameters on viral breakthrough at 1 year of therapy. ;

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Chronic Hepatitis B Virus Treatment
• Hepatitis B
• Hepatitis B, Chronic
• Hepatitis, Chronic

• NCT number: NCT01548820
• Study type: Observational
• Source: Ain Shams University
• Status: Completed
• Phase: N/A
• Start date: June 2010
• Completion date: January 2013