Decoding Chronic Pain With fMRI

Chronic Back Pain Clinical Trial

Official title:

Observational Study to Determine Abnormalities in Resting State fMRI in Chronic Back Pain.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01766973
• Other study ID #: CE-U.NA.NFLT.EGDF
• Status: Completed
• Start date: April 6, 2013
• Est. completion date: June 6, 2018

Study information

• Verified date: June 2018
• Source: University of Cambridge
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 76
• Est. completion date: June 6, 2018
• Est. primary completion date: April 6, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• age 18-60

• pain > 6months

• right-handed

• non-smoking

• mechanical back pain

Exclusion Criteria:

• significant neurological or psychiatric disease

• major systemic illness

• MRI exclusion criteria

Related Conditions & MeSH terms

• Back Pain
• Chronic Back Pain

Locations

Country	Name	City	State
United Kingdom	Addenbrookes Hospital	Cambridge

Sponsors (1)

Lead Sponsor	Collaborator
University of Cambridge

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Functional brain connectivity	Assessed by fMRI	6 months