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Clinical Trial Summary

This study will test the safety and efficacy of intra-arterial chemotherapy in subjects with newly diagnosed, residual, or recurrent atypical choroid plexus papilloma and choroid plexus carcinoma prior to a second surgery. It is believed that intra-arterial chemotherapy will be safe and feasible for this population and will result in decreased tumor size, which may further improve the goals of a second-look surgery.


Clinical Trial Description

The intent of this study is to determine if intra-arterial chemotherapy is a safe and effective option for subjects with atypical choroid plexus papilloma and choroid plexus carcinoma prior to receiving second-look surgery. Angiography occurs when a catheter is inserted through the subjects vasculature to the major vessels that supply cerebral circulation. Subjects on this trial will undergo a a cerebral angiogram to determine the ideal arteries to use for drug infusion. Once identified, chemotherapy will be delivered through the catheter directly to the site of tumor. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04994977
Study type Interventional
Source Weill Medical College of Cornell University
Contact Mark Souweidane, M.D.
Phone 212-746-2363
Email mmsouwei@med.cornell.edu
Status Recruiting
Phase Phase 1
Start date May 4, 2023
Completion date December 2026

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