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Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease — SACRO  

Chordoma Clinical Trial

Official title:
Title of Study: SAcral Chordoma: a Randomized & Observational Study on Surgery Versus Definitive Radiation Therapy in Primary Localized Disease (SACRO)

Clinical Trial Summary

Comparative study on surgery versus definitive radiation therapy in primary localized sacral chordoma

Clinical Trial Description

International, multicenter, comparative, open-label, parallel-group, mixed Observational-Randomized Controlled Trial. All the patients, who are candidate for the study will receive full information on the characteristics, potential effectiveness and side effects of the two alternatives treatments: radiotherapy (RT) and surgical treatment Eligible patients will be asked to be randomized in order to receive treatment A (surgery, with or without RT) or treatment B (definitive RT) Who will refuse randomization will be included in the Prospective Cohort Study (PCS) and will be treated accordingly to their choice (treatment option A or treatment option B). The same radiotherapy and surgical regimen will be administered in the PCS and in the Randomized Clinical Trial (RCT) cohort ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02986516
Study type Interventional
Source Italian Sarcoma Group
Contact Alessandro Gronchi, MD
Phone +390223903714
Email alessandro.gronchi@istitutotumori.mi.it
Status Recruiting
Phase N/A
Start date March 16, 2017
Completion date September 2024
View Details
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