Role of the Right Portal Pedicle and Rouviere's Sulcus as an Anatomic Landmark in Laparoscopic Cholecystectomy

Cholecystitis Clinical Trial

Official title:

Role of the Right Portal Pedicle and Rouviere's Sulcus as an Anatomic Landmark in Laparoscopic Cholecystectomy in Chinese Population

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02133027
• Other study ID #: Fanyingfang3
• Status: Recruiting
• Phase: N/A
• First received: April 28, 2014
• Last updated: May 3, 2014
• Start date: April 2014
• Est. completion date: April 2015

Study information

• Verified date: May 2014
• Source: Zhujiang Hospital
• Contact: Wang li qing, Doctor
• Phone: +86-02062783391
• Email: wliqing07[@]gmail.com
• Is FDA regulated: No
• Health authority: China: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

Objective:To explore the role of the right portal pedicle and Rouviere's sulcus as an anatomic landmark in laparoscopic cholecystectomy.

Methods:The investigators are going to select 60 patients intending to perform Laparoscopic cholecystectomy from April 2014 to April 2015.Check out the presence of the right portal pedicle and Rouviere's sulcus during the surgery and divide into the experimental group and the control group.Experimental group operated in Laparoscopic cholecystectomy with the guide of Rouviere's sulcus while the Control group operated with the traditional way.

Research hypothesis:Compare the differences between the Experimental group and the Control group in bile duct injury rate,complication rate,blood loss,operative time ,conversion rate and hospital stay.It is supposed that the results of Experimental group are superior to the control group,difference is statistically significant(P<0.05). So the investigators can draw the conclusion that the anatomy method with the guide of right portal pedicle and Rouviere's sulcus is useful in laparoscopic cholecystectomy.

Description:

Surgical procedures(Experimental group ):Placing the grasping forceps on the neck of the gallbladder, then retracted upwards and towards the left, so that the posterior aspect of the hepatobiliary triangle is exposed. the sulcus is seen running to the right of the hilum . In some patients, the lips of the sulcus are partially fused, with only a small cleft visible laterally. The sulcus indicates reliably the plane of the common bile duct; dissection may be started safely by division of the peritoneum immediately ventral to the sulcus and continued in a triangle bounded by the liver surface, the neck of the gallbladder and the plane of the sulcus. Even if the bile duct is tented upwards by the traction that has been exerted on the gallbladder, dissection will be safely ventral to the plane of the duct. Posterior branches of the cystic artery, may lie in the area of dissection and must be identified with care.Once a plane has been opened posteriorly, attention may be turned to the anterior dissection, using the posterior landmarks as a guide. The anterior and posterior dissections can then be made to meet, thus opening the hepatobiliary triangle completely.

Surgical procedures(Control group ):A small periumbilical incision is made, with the location and orientation depending on the patient's body habitus and cosmetic considerations.The laparoscope is used to explore the abdomen for adhesions and potential injuries that may have occurred during port placement，ratcheted grasper is inserted through the lateral 5-mm port to retract the gallbladder fundus in cephalad fashion. An atraumatic grasper is inserted through the middle 5-mm port to retract the gallbladder infundibulum laterally, exposing the anteromedial aspect of the triangle of Calot. A hook cautery is used to carefully incise the peritoneum overlying the triangle of Calot, continuing along the medial aspect of the proximal gallbladder. As the infundibulum is retracted superomedially, peritoneum overlying the posterolateral aspect of the triangle of Calot is similarly incised using hook cautery. All remaining connective tissue is dissected out of the triangle of Calot using blunt dissection and hook cautery as needed to fully mobilize the gallbladder infundibulum.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: April 2015
• Est. primary completion date: April 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years to 75 Years

Eligibility

Inclusion Criteria:

• Symptomatic gallstones

• Gallstones>3cm in diameter

• Fulfilled gallstones

• Acute or chronic cholecystitis

• Acalculous cholecystitis

• Gallbladder polyps >10mm in diameter

• Symptomatic gallbladder polyps

• Gallbladder stones associated with polyps

• Porcelain gallbladder

• Gallstone pancreatitis

Exclusion Criteria:

• Suspicion of gallbladder cancer

• General condition is poor,inability to tolerate gallbladder cancer

• Important organ dysfunction

• Severe abdominal cavity adhesion

• Bleeding disorders,blood coagulation dysfunction

• Acute cholangitis with serious complications(gallbladder empyema,gangrene,perforation)

• Acute cholangitis

• Pregnancy(first or third trimester)

• Abdominal dysfunction or peritonitis

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Cholecystitis
• Gallstones
• Polyps

Intervention

Procedure:
• Rouviere's sulcus
Dissection may be started safely by division of the peritoneum immediately ventral to the sulcus and continued in a triangle bounded by the liver surface, the neck of the gallbladder and the plane of the sulcus.

Device:
• surgical instruments
surgical instruments used in the laparoscopic cholecystectomy,such as ratcheted grasper,atraumatic grasper ,scissors.

Locations

Country	Name	City	State
China	Department of Hepatobiliary (I),Zhujiang Hospital	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Zhujiang Hospital

Country where clinical trial is conducted

China, 

References & Publications (1)

Dahmane R, Morjane A, Starc A. Anatomy and surgical relevance of Rouviere's sulcus. ScientificWorldJournal. 2013 Nov 6;2013:254287. doi: 10.1155/2013/254287. eCollection 2013. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	hospital stay	The hospitalization time after operation	participants will be followed for the duration of hospital stay, an expected average of 1 weeks	No
Other	blood loss	the total amount of operation bleeding	From date of randomization until the date of first documented progression ,assessed up to 12 months	Yes
Primary	complication rate	biliary injury,artery injury etc.	one month	Yes
Secondary	conversion rate	The frequency of conversion to open surgery.	From date of randomization until the date of first documented progression ,assessed up to 12 months	Yes