Chlamydia Trachomatis Clinical Trial
— DECHLAGOOfficial title:
Time to Clearance of Chlamydia Trachomatis and Neisseria Gonorrhoeae RNA After Treatment: a Prospective Cohort Study
The aim of this study is to evaluate the negativation time of chlamydial and gonococcal PCRs after treatment for urogenital, oropharyngeal and anal infections.
Status | Not yet recruiting |
Enrollment | 140 |
Est. completion date | November 1, 2025 |
Est. primary completion date | November 1, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - - Patients attending the Trait d'Union department at the Nouvel Hôpital Civil for PrEP consultations, AES or HIV infection. - Over 18 years of age - Male or female - Who have had an uncomplicated CT and/or NG infection treated with currently recommended therapies (Ceftriaxone 500mg DU for NG infections, Doxycycline 200mg per day for 1 week for rectal CT infections and Azithromycin 1g DU or Doxycycline 7 days for other CT infections). - Subject affiliated to a social health insurance scheme - Subject able to understand the aims and risks of the research and to give dated and signed informed consent Exclusion Criteria: - - Complicated CT and/or NG infections: epididymitis, prostatitis, upper genital infection, extra-genital involvement (keratoconjunctivitis, arthritis, skin involvement, Fiessinger-Leroy-reiter syndrome, Fitz-Hugh-Curtis syndrome). - Interfering treatments and associated diseases: Severe immunosuppression (HIV infection with CD4 less than 200/mm3, chemotherapy in the last 6 months, active haemopathy, congenital immune deficiency, immunosuppressive treatment including corticosteroid therapy for more than 4 weeks or organ transplant. - Impossibility of giving the subject informed information (subject in an emergency situation, difficulties in understanding the subject, etc.). - Subject under court protection - Subject under guardianship or curatorship |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Strasbourg, France |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Estimate the rate of negativation of NAATs performed at the various sites of CT infection | 4 weeks after initiation of treatment |
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