Chlamydia Trachomatis Infection Clinical Trial
Official title:
Comparison of Efficacy of Two Combination Regimens for the Treatment of Uncomplicated Neisseria Gonorrhoeae and Chlamydia Trachomatis Coinfection
Verified date | January 2022 |
Source | Haiphong University of Medicine and Pharmacy |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The frequency of Chlamydia trachomatis and Neisseria gonorrhoeae coinfection can vary depending on their individual incidence and prevalence rates.Single-agent therapy with ceftriaxone is the preferred regimen for treatment of gonococcal infections. If an injectable cephalosporin is not available, cefixime is the only oral cephalosporin that can be used for gonococcal therapy. Doxycycline was recommended for presumptive treatment of chlamydia in nonpregnant individuals with gonococcal infection. The study is conducted to evaluate the effectiveness of two regimens in combination with doxycycline with cefixime or ceftriaxone.
Status | Completed |
Enrollment | 125 |
Est. completion date | February 20, 2022 |
Est. primary completion date | February 15, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Patient over 18 ages with laboratory-documented uncomplicated Chlamydia trachomatis and Neisseria gonorrhoeae reinfection at any site Exclusion Criteria: - Pregnancy - Breast feeding - Hypersensitivity to cephalosporins or penicillins - significant renal failure or hepatic failure |
Country | Name | City | State |
---|---|---|---|
Vietnam | Haiphong International Hospital | H?i Phòng |
Lead Sponsor | Collaborator |
---|---|
Haiphong University of Medicine and Pharmacy |
Vietnam,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | cure rate | a negative test of cure for Chlamydia trachomatis and Neisseria gonorrhoeae | 5th day after treatment | |
Secondary | Side effects | Any side effects from interventions in two arms | From 1st day of study to 5th day after treatment |
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