Children, Only Clinical Trial
Official title:
NT-proBNP and Troponin I in Children With Dengue Hemorrhagic Shock: a Longitudinal Study
NCT number | NCT04837430 |
Other study ID # | 2130-DHYD |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | April 2, 2021 |
Est. completion date | December 31, 2023 |
To discribe concentration of NT-proBNP and Troponin I in Dengue hemorrhagic shock children, in correlation between concentration of NT-proBNP and troponin I with total fluid admission, respiratory support, using inotrope and vasopressor using.
Status | Recruiting |
Enrollment | 90 |
Est. completion date | December 31, 2023 |
Est. primary completion date | December 31, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 1 Month to 18 Years |
Eligibility | Inclusion Criteria: - Dengue shock children who admitted to ICU Exclusion Criteria: - Excluding the cases of children with cardiovascular disease, hyperthyroidism, taking drugs such as insulin, steroid, estrogen, growth hormone, thyroid hormone |
Country | Name | City | State |
---|---|---|---|
Vietnam | University of medicine and pharmacy at Ho Chi Minh city | Ho Chi Minh City |
Lead Sponsor | Collaborator |
---|---|
Le Phuoc Truyen |
Vietnam,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Concentration of NT-proBNP | Concentration of NT-proBNP in Children with Dengue hemorrhagic shock and severe shock | 10 days | |
Primary | Concentration of Troponin I | Concentration of Troponin I in Children with Dengue hemorrhagic shock and severe shock | 10 days | |
Secondary | Cut-off value of NT-proBNP for fluid overload | Cut-off value of NT-proBNP for pulmonary edema | 14 days | |
Secondary | Correlation between concentration of NT-proBNP | Correlation between concentration of NT-proBNP with total fluid admission, respiratory support, using inotrope and vasopressor using | 14 days | |
Secondary | Correlation between concentration of Troponin I | Correlation between concentration of Troponin I total fluid admission, respiratory support, using inotrope and vasopressor using | 14 days | |
Secondary | Rate of clinical manifestations | Rate of clinical manifestations: fever, abdominal pain, petechia, hematomegaly | 14 days | |
Secondary | Rate of abnormal laboratory exam | electrolyte, arterial blood gas, lactate | 14 days | |
Secondary | Rate of abnormal liver, kidney, hematology laboratory exam | AST, ALT, ure, creatinin, PLT, PT, aPTT, Fibrinogen | 14 days | |
Secondary | Rate of NS1 Dengue | Positive | 10 days | |
Secondary | Rate of MAC ELISA IgM Dengue | Positive | 14 days | |
Secondary | Rate of complications | Pulmonary edema | 14 days | |
Secondary | Rate of respiratory support | Cannula, NCPAP, Intubation | 14 days | |
Secondary | Rate of intubation | Positive | 14 days | |
Secondary | Rate of mode of ventilation | PC, IP, PEEP, FiO2, VT | 14 days | |
Secondary | Total fluid administration | ml/kg/d | 14 days | |
Secondary | Time for IV fluid administration | hours | 14 days | |
Secondary | Rate and kind of cephalosporin using | 3rd generation cephalosporin | 14 days | |
Secondary | Rate and kind of Carbapenem using | Carbapenem | 14 days | |
Secondary | Rate and kind of Vancomycin using | Vancomycin | 14 days | |
Secondary | Rate of intraperitoneal fluid drainage | Positive | 14 days | |
Secondary | Rate of CRRT | Positive | 14 days |
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT03781817 -
Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures
|
Phase 4 | |
Recruiting |
NCT05424757 -
Polyethylene Glycol Safety in Children
|
||
Recruiting |
NCT04602429 -
Children's Acute Surgical Abdomen Programme
|
||
Recruiting |
NCT05378581 -
Use of Virtual Reality Mask During Blood and Skin Allergic Tests in 7 to 13 Children
|
N/A | |
Completed |
NCT04933734 -
Turkish Cultural Adaptation, Validity and Reliability of the "Physical Activity-Specific Rumination Scale for Children"
|
||
Completed |
NCT03457688 -
Effect of Prebiotic Fructans to Reduce Number of Febrile Infections in Children
|
N/A | |
Recruiting |
NCT05113420 -
The Efficacy and Safety of Different Phlebotonic Drugs in Children With Venous Malformations
|
||
Completed |
NCT03241355 -
Prebiotic Fructans on the Incidence of Acute Infectious Diseases in Children
|
N/A | |
Not yet recruiting |
NCT05484102 -
Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children
|
N/A | |
Recruiting |
NCT04460313 -
Nasopharyngeal Carriage of S. Pneumoniae
|
N/A | |
Not yet recruiting |
NCT05974917 -
Serious gaMes as Emerging E-health Interventions for Young People With neurologicaL or rEspiratory disoRders
|
||
Completed |
NCT06451289 -
Study on Optic Nerve Sheath Diameter Measurements in Prolonged Pediatric Seizures
|
||
Completed |
NCT04057612 -
Correlation Between Core Temperature and Skin Temperature in Pediatrics
|
||
Completed |
NCT04256590 -
Tongue Depressor-related Tongue Swelling
|
||
Recruiting |
NCT03319927 -
Reducing Pesticide Exposures in Child Care Centers
|
N/A | |
Enrolling by invitation |
NCT05513235 -
Feasibility Study of a Mobile Digital Personal Health Record for Family-Centered Care Coordination for Children and Youth With Special Healthcare Needs
|
N/A | |
Completed |
NCT04615000 -
SeroCovid<19: Covid-19 Seroconversion in Tertiary Pediatric Patients
|
||
Not yet recruiting |
NCT05568849 -
Optical Coherence Tomography Angiography (OCTA) in Children's Cardiac Surgery
|
N/A | |
Recruiting |
NCT06157346 -
Characteristics of Intestinal Bacteria and Their Effects on Growth and Immune Function in Children at High Altitude
|
||
Recruiting |
NCT04206956 -
Anxiety and Chronic Postsurgical Pain Following Ambulatory Surgery in Children
|