Children, Only Clinical Trial
Official title:
Reducing Pesticide Exposures to Preschool-age Children in California Child Care Centers
To reduce the risk of adverse health problems associated with chronic exposure to pesticides, a randomized control study will evaluate a nurse-led integrated pest management (IPM) intervention in 88 child care centers serving socio-economically and ethnically diverse preschool-age children in four California counties. Positive changes in IPM knowledge, policies, practices, pests, and pesticide exposure will be assessed.
Status | Recruiting |
Enrollment | 440 |
Est. completion date | August 31, 2024 |
Est. primary completion date | August 31, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 3 Years to 75 Years |
Eligibility | Inclusion Criteria: The centers must meet the following criteria: 1. Be a licensed child care center with a child care director who speaks English 2. Used pesticides (i.e., baits or sprays) in the last year 3. Operated for at least two years with no plans to close in the next 12 months 4. Enroll children between three to five years of age of diverse ethnic and racial backgrounds 5. Have at least 25% of enrolled children receiving a government subsidy (e.g., Child and Adult Care Food Program (CACFP), Head Start, Child Care Development Fund, Alternative Payment program). 6. Have a carpet or couch on-site. The child care providers must meet the following criteria: 1. Work in the participating child care centers 2. Work in the classroom of the participating children 3. Work at least 30 hours a week 4. Plan to work at the center over the next 9 months The families must have a preschool-age child enrolled in the participating child care center and meet the following criteria: 1. Three or four years of age 2. The child spends at least six hours per day in the center 3. Will be enrolled in the center for the next nine months 4. Has a parent present during enrollment who speaks either English or Spanish 5. Parents will complete surveys or interviews in English or Spanish in the Fall and Spring Exclusion Criteria: 1. Centers that participated in an IPM intervention and training project 2. Families that have children who have special health care needs or disabilities who can not participate in physical activity at the child care center. 3. Center directors who do not read and write in English. 4. Child care providers who do not read and write in English. |
Country | Name | City | State |
---|---|---|---|
United States | University of California, San Francisco | San Francisco | California |
Lead Sponsor | Collaborator |
---|---|
University of California, San Francisco | National Institute of Environmental Health Sciences (NIEHS), Oregon State University, University of California, Berkeley |
United States,
Alkon A, Gunier RB, Hazard K, Castorina R, Hoffman PD, Scott RP, Anderson KA, Bradman A. Preschool-Age Children's Pesticide Exposures in Child Care Centers and at Home in Northern California. J Pediatr Health Care. 2022 Jan-Feb;36(1):34-45. doi: 10.1016/j — View Citation
Alkon A, Nouredini S, Swartz A, Sutherland AM, Stephens M, Davidson NA, Rose R. Integrated Pest Management Intervention in Child Care Centers Improves Knowledge, Pest Control, and Practices. J Pediatr Health Care. 2016 Nov-Dec;30(6):e27-e41. doi: 10.1016/j.pedhc.2016.07.004. Epub 2016 Aug 20. — View Citation
Bradman, A, Gasper, F, Castorina, R, Tong-Lin, E, McKone, T, & Maddelena, R. (2012). Environmental exposures in early childhood education environments (Agreement Number 08-305). Retrieved from Berkeley, CA:
Hazard K, Alkon A, Gunier RB, Castorina R, Camann D, Quarderer S, Bradman A. Predictors of pesticide levels in carpet dust collected from child care centers in Northern California, USA. J Expo Sci Environ Epidemiol. 2023 Jan 4:1-12. doi: 10.1038/s41370-02 — View Citation
Vidi PA, Anderson KA, Chen H, Anderson R, Salvador-Moreno N, Mora DC, Poutasse C, Laurienti PJ, Daniel SS, Arcury TA. Personal samplers of bioavailable pesticides integrated with a hair follicle assay of DNA damage to assess environmental exposures and their associated risks in children. Mutat Res Genet Toxicol Environ Mutagen. 2017 Oct;822:27-33. doi: 10.1016/j.mrgentox.2017.07.003. Epub 2017 Jul 16. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Change in knowledge | Change in responses to a multiple choice survey on content covered in the workshops from pre- to post-workshop | pre- and immediately after the workshop is completed | |
Other | Change in child body mass index (BMI) | Collect children's height in cm and weight in meters and calculate BMI (kg/(meter squared)) | Before the educational workshop and 9 months after the workshop | |
Primary | Change in child care center pesticide exposures | Change in the levels of pesticide exposures collected in dust samples in the child care centers from baseline to 9 months later. Pesticides will be summarized as mean concentration (ng/g) and loading (ng/m2). | Before the educational workshop and 9 months after the workshop | |
Primary | Change in personal pesticide exposures | Change in the levels of pesticide exposures collected in personal silicone wristbands from baseline to 9 months later. Pesticides will be summarized as mean concentration (ng/mL). | Before the educational workshop and 9 months after the workshop | |
Secondary | Change in integrated pest management (IPM) practices | a. Change in the IPM policies and practices identified during a 2-hour observational assessment using a standardized Policies Checklist and IPM Checklist to assess level of IPM practices from baseline to 9 months later.. | Before the educational workshop and 9 months after the workshop | |
Secondary | Change in the presence of pests or evidence of pests | Change in the observed # of pests or evidence of pests as part of the IPM Checklist assessment from baseline to 9 months later. | Before the educational workshop and 9 months after the workshop | |
Secondary | Change in integrated pest management (IPM) policies | a. Change in the IPM policies identified during an assessment using a standardized Policies Checklist to assess presence of written IPM policy and if present, the quality of the IPM policy. | Before the educational workshop and 9 months after the workshop |
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