Clinical Trial Details
— Status: Enrolling by invitation
Administrative data
NCT number |
NCT00795080 |
Other study ID # |
HUM 18481 |
Secondary ID |
|
Status |
Enrolling by invitation |
Phase |
|
First received |
|
Last updated |
|
Start date |
July 15, 2012 |
Est. completion date |
December 2024 |
Study information
Verified date |
November 2023 |
Source |
University of Michigan |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational
|
Clinical Trial Summary
The purpose of this study is to decide which position of the neck affects cerebral spinal
fluid (CSF) flow between the spinal cord and the brain. CSF is a fluid that flows up and down
your spinal cord, around the brain and into the ventricles of the brain.
This study will be done with patients who have abnormalities of the neck, including Chiari 1
malformations.
Description:
In this study, subjects will have a dynamic cervical magnetic resonance imaging (MRI) of the
craniovertebral junction (CVJ) coupled with CSF flow studies. The studies will assess changes
in CSF flow velocities that are associated with with changing position of the neck at the CVJ
and aqueduct of Sylvius.
Eligible patients include those with Chiari 1 malformations and similar malformations to the
CVJ. This malformation lead to inherent instability in this region and symptoms such as
headaches, dizziness, neck pain and other neurological problems. This study will determine if
there is any correlation of these MRI findings to clinical outcome.