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Non-invasive Left Ventricle Contractility dp/dt as Prognostic Marker in Chest Unit Patients — dp/dt  

Chest Pain Clinical Trial

Official title:
Non Invasive Left Ventricle Contractility dp/dt Could be Used as a Prognostic Marker in Patients Admitted to the Emergency Department for Chest Pain

Clinical Trial Summary

Ischemic heart disease is a major public health problem with high mortality rate despite the progress in management and the resources mobilized. The idea is that myocardial ischemia is generally associated with left ventricular dysfunction and, consequently, a possible alteration of the dp/dt index. As dp/dt could be assessed non-invasively by plethysmographic method, it is interesting to investigate its prognostic performance in patients with indifferentiate chest pain.

Clinical Trial Description

Ischemic heart disease remains a major public health problem. Despite all the advances in the prognostic approach to ischemic heart disease, the risk of occurrence of major cardiovascular events is not negligible. Several scores have been proposed for chest pain stratification risk, the most widely used are the TIMI and the GRACE scores. The dP/dt max is therefore an excellent index of contractility, corresponding to the maximum level of tension developed by an isolated cardiac muscle during the isovolumic contraction phase. the investigator theorized that a less value of dp/dt would be associated with more major cardiovascular events (MACE), because ischemia reduces myocardial contractility. The current study describes non-invasive plethysmographic dp/dt changes, which could be used as a prognostic marker in patients presenting at the emergency department with acute chest pain. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05416112
Study type Observational [Patient Registry]
Source University of Monastir
Contact Nouira Semir, professor
Phone 73106046
Email semir.nouira@rns.tn
Status Recruiting
Phase
Start date June 1, 2022
Completion date September 30, 2023
View Details
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